8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)

Modify Date: 2026-08-07 12:41:31

8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS) structure	Common Name	8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)
	CAS Number	507-79-9	Molecular Weight	331.36300
	Density	1.41g/cm3	Boiling Point	494.2ºC at 760mmHg
	Molecular Formula	C₁₈H₂₁NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	252.7ºC

Use of 8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)

Tazettine is an alkaloid with low cytotoxicity to mammalian cell lines (CC50 >100 μg/mL)[1].

Summary: Tazettine, Chinese name: 8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-(3S,4aS,6aS,13bS)-, CAS number: 507-79-9, molecular formula: C18H21NO5, molecular weight: 331.36300. For research-use only, not for medical or clinical usage.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	tazettine
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	Tazettine is an alkaloid with low cytotoxicity to mammalian cell lines (CC50 >100 μg/mL)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Brine ND, et al. A dinitrogenous alkaloid from Cyrtanthus obliquus. Phytochemistry. 2002 Oct;61(4):443-7.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.41g/cm3
Boiling Point	494.2ºC at 760mmHg
Molecular Formula	C₁₈H₂₁NO₅
Molecular Weight	331.36300
Flash Point	252.7ºC
Exact Mass	331.14200
PSA	60.39000
LogP	1.09870
Index of Refraction	1.66
InChIKey	YLWAQARRNQVEHD-UHFFFAOYSA-N
SMILES	COC1C=CC23c4cc5c(cc4COC2(O)CN(C)C3C1)OCO5

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 0
DownStream 2
CAS#:65367-81-9 [1,3]Dioxolo[4,... CAS#:40141-98-8 5-methyl-[1,3]d...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: HT-29
External Id: CHEMBL2214240

Name: Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: A549
External Id: CHEMBL2214241

Name: Cytotoxicity against human Jurkat cells assessed as cell growth at 10 uM measured aft...
Source: ChEMBL
Target: Jurkat
External Id: CHEMBL5589474

Name: Cytotoxicity against human MOLT-4 cells assessed as cell growth at 10 uM measured aft...
Source: ChEMBL
Target: MOLT-4
External Id: CHEMBL5589475

Name: Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: HL-60
External Id: CHEMBL2214244

Name: Cytotoxicity against human A549 cells assessed as cell growth at 10 uM measured after...
Source: ChEMBL
Target: A549
External Id: CHEMBL5589476

Name: Cytotoxicity against human HT-29 cells assessed as cell growth at 10 uM measured afte...
Source: ChEMBL
Target: HT-29
External Id: CHEMBL5589477

Name: Inhibition of AChE at 10 uM by Ellman's assay
Source: ChEMBL
Target: Acetylcholinesterase
External Id: CHEMBL1227598

Name: Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: HepG2
External Id: CHEMBL2214242

Name: Cytotoxicity against human PANC-1 cells assessed as cell growth at 10 uM measured aft...
Source: ChEMBL
Target: PANC-1
External Id: CHEMBL5589478

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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

sekisanoline

(4aS)-3c-methoxy-5-methyl-(4ar,13btC1)-4,4a,5,6-tetrahydro-3H,8H-[1,3]dioxolo[4',5':6,7]isochromeno[3,4-c]indol-6at-ol

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the InChIKey of tazettine?

A: InChIKey of tazettine is YLWAQARRNQVEHD-UHFFFAOYSA-N.

Q: What is the LogP of tazettine?

A: LogP of tazettine is 1.09870.

Q: What are the downstream products of tazettine?

A: Related downstream products(CAS) of tazettine: 65367-81-9;40141-98-8.

Q: What is the polar surface area (PSA) of tazettine?

A: Polar surface area (PSA) of tazettine is 60.39000.

Q: What are the uses of tazettine?

A: Main uses of tazettine: Tazettine is an alkaloid with low cytotoxicity to mammalian cell lines (CC50 >100 μg/mL)[1].

Q: What is the boiling point of tazettine?

A: Boiling point of tazettine is 494.2ºC at 760mmHg.

Q: What is the English name of tazettine?

A: The English name of tazettine is tazettine.

Q: What English synonyms does tazettine have?

A: English synonyms of tazettine: sekisanoline, (4aS)-3c-methoxy-5-methyl-(4ar,13btC1)-4,4a,5,6-tetrahydro-3H,8H-[1,3]dioxolo[4',5':6,7]isochromeno[3,4-c]indol-6at-ol.

Q: What is the molecular formula of tazettine?

A: Molecular formula of tazettine is C18H21NO5.

Q: What is the CAS number of tazettine?

A: CAS number of tazettine is 507-79-9.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)

Use of 8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)

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