8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)

Modify Date: 2025-08-25 10:03:43

8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS) Structure
8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS) structure
Common Name 8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)
CAS Number 507-79-9 Molecular Weight 331.36300
Density 1.41g/cm3 Boiling Point 494.2ºC at 760mmHg
Molecular Formula C18H21NO5 Melting Point N/A
MSDS N/A Flash Point 252.7ºC

 Use of 8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)


Tazettine is an alkaloid with low cytotoxicity to mammalian cell lines (CC50 >100 μg/mL)[1].

 Names

Name tazettine
Synonym More Synonyms

  Biological Activity

Description Tazettine is an alkaloid with low cytotoxicity to mammalian cell lines (CC50 >100 μg/mL)[1].
Related Catalog
References

[1]. Brine ND, et al. A dinitrogenous alkaloid from Cyrtanthus obliquus. Phytochemistry. 2002 Oct;61(4):443-7.  

 Chemical & Physical Properties

Density 1.41g/cm3
Boiling Point 494.2ºC at 760mmHg
Molecular Formula C18H21NO5
Molecular Weight 331.36300
Flash Point 252.7ºC
Exact Mass 331.14200
PSA 60.39000
LogP 1.09870
Index of Refraction 1.66
InChIKey YLWAQARRNQVEHD-UHFFFAOYSA-N
SMILES COC1C=CC23c4cc5c(cc4COC2(O)CN(C)C3C1)OCO5

 Precursor & DownStream

Precursor  0

DownStream  2

 Bioassay

View more

Name: Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: HT-29
External Id: CHEMBL2214240
Name: Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: A549
External Id: CHEMBL2214241
Name: Cytotoxicity against human Jurkat cells assessed as cell growth at 10 uM measured aft...
Source: ChEMBL
Target: Jurkat
External Id: CHEMBL5589474
Name: Cytotoxicity against human MOLT-4 cells assessed as cell growth at 10 uM measured aft...
Source: ChEMBL
Target: MOLT-4
External Id: CHEMBL5589475
Name: Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: HL-60
External Id: CHEMBL2214244
Name: Cytotoxicity against human A549 cells assessed as cell growth at 10 uM measured after...
Source: ChEMBL
Target: A549
External Id: CHEMBL5589476
Name: Cytotoxicity against human HT-29 cells assessed as cell growth at 10 uM measured afte...
Source: ChEMBL
Target: HT-29
External Id: CHEMBL5589477
Name: Inhibition of AChE at 10 uM by Ellman's assay
Source: ChEMBL
Target: Acetylcholinesterase
External Id: CHEMBL1227598
Name: Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: HepG2
External Id: CHEMBL2214242
Name: Cytotoxicity against human PANC-1 cells assessed as cell growth at 10 uM measured aft...
Source: ChEMBL
Target: PANC-1
External Id: CHEMBL5589478
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 Synonyms

sekisanoline
(4aS)-3c-methoxy-5-methyl-(4ar,13btC1)-4,4a,5,6-tetrahydro-3H,8H-[1,3]dioxolo[4',5':6,7]isochromeno[3,4-c]indol-6at-ol
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