NY-ESO-1 (87-111)

Modify Date: 2024-01-09 11:16:00

NY-ESO-1 (87-111) Structure
NY-ESO-1 (87-111) structure
Common Name NY-ESO-1 (87-111)
CAS Number 508230-31-7 Molecular Weight 2869.40
Density N/A Boiling Point N/A
Molecular Formula C131H206N32O36S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NY-ESO-1 (87-111)


NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide sequence. NY-ESO-1 (87-111) binds to multiple HLA-DR and HLA-DP4 molecules, and stimulates Th1-type and Th-2/Th0-type CD4+ T cells when presented in the context of HLA-DR and HLA-DP4 molecules[1].

 Names

Name NY-ESO-1 (87-111)

 NY-ESO-1 (87-111) Biological Activity

Description NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide sequence. NY-ESO-1 (87-111) binds to multiple HLA-DR and HLA-DP4 molecules, and stimulates Th1-type and Th-2/Th0-type CD4+ T cells when presented in the context of HLA-DR and HLA-DP4 molecules[1].
Related Catalog
References

[1]. Maja Mandic, et al. One NY-ESO-1-derived epitope that promiscuously binds to multiple HLA-DR and HLA-DP4 molecules and stimulates autologous CD4+ T cells from patients with NY-ESO-1-expressing melanoma. J Immunol. 2005 Feb 1;174(3):1751-9.

 Chemical & Physical Properties

Molecular Formula C131H206N32O36S2
Molecular Weight 2869.40
InChIKey OTOOPFZEJTVSTP-IMEIIJQSSA-N
SMILES CSCCC(NC(=O)C1CCCN1C(=O)C(NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C1CCCN1C(=O)C(CCSC)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(N)CC(C)C)C(C)O)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCC(N)=O)C(=O)O
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