Disodium protoporphyrin IX

Modify Date: 2025-08-23 13:12:20

Disodium protoporphyrin IX Structure
Disodium protoporphyrin IX structure
Common Name Disodium protoporphyrin IX
CAS Number 50865-01-5 Molecular Weight 606.622
Density N/A Boiling Point 1128.9ºC at 760 mmHg
Molecular Formula C34H32N4Na2O4 Melting Point N/A
MSDS USA Flash Point 636.6ºC

 Names

Name Zinc Ionophore II
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 1128.9ºC at 760 mmHg
Molecular Formula C34H32N4Na2O4
Molecular Weight 606.622
Flash Point 636.6ºC
Exact Mass 606.221924
PSA 136.56000
LogP 1.37120
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TS5450000
CHEMICAL NAME :
21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, disodium salt
CAS REGISTRY NUMBER :
50865-01-5
LAST UPDATED :
199806
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C34-H32-N4-O4.2Na
MOLECULAR WEIGHT :
606.68

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
240 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,729,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,1192,1995
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1029 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,729,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1147 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,729,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
484 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,729,1982

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS TS5450000

 Articles50

More Articles
Protein structure. Structure and activity of tryptophan-rich TSPO proteins.

Science 347(6221) , 551-5, (2015)

Translocator proteins (TSPOs) bind steroids and porphyrins, and they are implicated in many human diseases, for which they serve as biomarkers and therapeutic targets. TSPOs have tryptophan-rich seque...

Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy.

Nat. Med. 19(4) , 418-20, (2013)

Co-therapy with rifampicin (RIF) and isoniazid (INH) used to treat tuberculosis in humans frequently causes liver injury. Here, using a pregnane X receptor (PXR)-humanized mouse model, we found that c...

Salicylic acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity.

Mol. Pharmacol. 84(6) , 824-33, (2013)

Salicylic acid is a classic nonsteroidal anti-inflammatory drug. Although salicylic acid also induces mitochondrial injury, the mechanism of its antimitochondrial activity is not well understood. In t...

 Synonyms

EINECS 256-815-9
21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, sodium salt (1:2)
Disodium 3,3'-(3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphyrindiyl)dipropanoate
MFCD00151108
Disodium protoporphyrin IX
Disodium 3,3'-(3,7,12,17-tetramethyl-8,13-divinylporphyrin-2,18-diyl)dipropanoate
7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic Acid Disodium Salt
Protoporphyrin DisodiuM Salt
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