Acetomycin

Modify Date: 2024-01-24 20:19:35

Acetomycin Structure
Acetomycin structure
Common Name Acetomycin
CAS Number 510-18-9 Molecular Weight 214.22
Density 1.18g/cm3 Boiling Point 336.2ºC at 760mmHg
Molecular Formula C10H14O5 Melting Point N/A
MSDS N/A Flash Point 148.9ºC

 Use of Acetomycin


Acetomycin is an antibiotic. Acetomycin inhibits the growth of CT-8 human colon adenocarcinoma cells (IC50: 1.5 μg/mL) and L1210 murine leukemia cells (IC50: 2.2 μg/mL). Acetomycin can be isolated from actinomycete WP-2661[1].

 Names

Name 2(3H)-Furanone, 3-acetyl-5-(acetyloxy)dihydro-3,4-dimethyl
Synonym More Synonyms

 Acetomycin Biological Activity

Description Acetomycin is an antibiotic. Acetomycin inhibits the growth of CT-8 human colon adenocarcinoma cells (IC50: 1.5 μg/mL) and L1210 murine leukemia cells (IC50: 2.2 μg/mL). Acetomycin can be isolated from actinomycete WP-2661[1].
Related Catalog
References

[1]. Mamber SW, et al. Biological effects of acetomycin. I. Activity against tumor cells in vitro and in vivo. J Antibiot (Tokyo). 1987 Jan;40(1):73-6.  

 Chemical & Physical Properties

Density 1.18g/cm3
Boiling Point 336.2ºC at 760mmHg
Molecular Formula C10H14O5
Molecular Weight 214.22
Flash Point 148.9ºC
Exact Mass 214.08400
PSA 69.67000
LogP 0.66380
Index of Refraction 1.466

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AL2850000
CHEMICAL NAME :
Acetomycin
CAS REGISTRY NUMBER :
510-18-9
BEILSTEIN REFERENCE NO. :
0174279
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H14-O5
MOLECULAR WEIGHT :
214.24
WISWESSER LINE NOTATION :
T5OVTJ CV1 C1 D1 EOV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 2,905,1978

 Safety Information

HS Code 2932190090

 Customs

HS Code 2932190090
Summary 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

acetomycin
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