2-n-BUTYL-3-DIMETHYLAMINO-5,6-METHYL-ENE DIOXYINDENE HYDROCHLORIDE

Modify Date: 2024-10-10 12:33:16

2-n-BUTYL-3-DIMETHYLAMINO-5,6-METHYL-ENE DIOXYINDENE HYDROCHLORIDE structure	Common Name	2-n-BUTYL-3-DIMETHYLAMINO-5,6-METHYL-ENE DIOXYINDENE HYDROCHLORIDE
	CAS Number	51003-83-9	Molecular Weight	295.80400
	Density	1.13g/cm3	Boiling Point	367.6ºC at 760 mmHg
	Molecular Formula	C₁₆H₂₂ClNO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	126.5ºC

Name	6-butyl-N,N-dimethyl-7H-cyclopenta[f][1,3]benzodioxol-7-amine,hydrochloride
Synonym	More Synonyms

Density	1.13g/cm3
Boiling Point	367.6ºC at 760 mmHg
Molecular Formula	C₁₆H₂₂ClNO₂
Molecular Weight	295.80400
Flash Point	126.5ºC
Exact Mass	295.13400
PSA	21.70000
LogP	4.40720
Index of Refraction	1.581

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NK8926000

CHEMICAL NAME :: 5H-Indeno(5,6-d)-1,3-dioxole, 6-butyl-5-dimethylamino-, hydrochloride

CAS REGISTRY NUMBER :: 51003-83-9

LAST UPDATED :: 199606

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C16-H21-N-O2.Cl-H

MOLECULAR WEIGHT :: 295.84

WISWESSER LINE NOTATION :: T C565 DO FO EH JHJ JN1&1 K4 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Gastrointestinal - decreased motility or constipation

REFERENCE :: RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 185 mg/kg

TOXIC EFFECTS :: Gastrointestinal - decreased motility or constipation

REFERENCE :: RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) Gastrointestinal - decreased motility or constipation

REFERENCE :: RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 735 mg/kg/4W-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

REFERENCE :: RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 647 mg/kg/2W-I

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979

2-Butyl-5,6-methylenedioxyindene-1-dimethylammonium hydrochloride

2-n-Butyl-3-dimethylamino-5,6-methylenedioxyindenehydrochloride

bu-MDI

bu-MDI HCl