Substance P (5-11) trifluoroacetate salt

Modify Date: 2025-08-25 14:31:22

Substance P (5-11) trifluoroacetate salt Structure
Substance P (5-11) trifluoroacetate salt structure
Common Name Substance P (5-11) trifluoroacetate salt
CAS Number 51165-09-4 Molecular Weight 869.04200
Density 1.265g/cm3 Boiling Point 1375.5ºC at 760 mmHg
Molecular Formula C41H60N10O9S Melting Point N/A
MSDS N/A Flash Point 785.6ºC

 Use of Substance P (5-11) trifluoroacetate salt


Substance P (5-11), the C-terminal heptapeptide of Substance P (Substance P (HY-P0201)), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor[1].

 Names

Name substance p (5-11)
Synonym More Synonyms

 Substance P (5-11) trifluoroacetate salt Biological Activity

Description Substance P (5-11), the C-terminal heptapeptide of Substance P (Substance P (HY-P0201)), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor[1].
Related Catalog
In Vitro 当将富含神经胶质细胞的兔脑部分与 [3H]Substance P (5-11) 一起孵育时,观察到 [3H]Substance P (5-11) 的摄取。当 Substance P 从神经末梢释放时,它被水解成 Substance P (5-11),后者又积聚到神经胶质细胞和神经末梢,这种高亲和力摄取机制可能在终止突触过程中发挥重要作用[1]。
References

[1]. A Inoue, et al. Active uptake system for substance P carboxy-terminal heptapeptide (5-11) into a fraction from rabbit enriched in glial cells. Jpn J Pharmacol. 1984 Oct;36(2):137-45.  

 Chemical & Physical Properties

Density 1.265g/cm3
Boiling Point 1375.5ºC at 760 mmHg
Molecular Formula C41H60N10O9S
Molecular Weight 869.04200
Flash Point 785.6ºC
Exact Mass 868.42700
PSA 355.19000
LogP 3.30140
Index of Refraction 1.581

 Synonyms

L-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2
Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
L-Glu(NH2)-L-Glu(NH2)-L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2
H-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
HEPTA-SUBSTANCE P
Substance-P-(5-11) Hepta-Substance P
substance P fragment 5-11
substance P5-11
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