(1R)-6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol,chloride

Modify Date: 2024-01-11 11:01:59

(1R)-6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol,chloride structure	Common Name	(1R)-6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol,chloride
	CAS Number	51713-80-5	Molecular Weight	243.73000
	Density	N/A	Boiling Point	319.1ºC at 760 mmHg
	Molecular Formula	C₁₂H₁₈ClNO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	146.8ºC

Name	(1R)-6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol,chloride

Boiling Point	319.1ºC at 760 mmHg
Molecular Formula	C₁₂H₁₈ClNO₂
Molecular Weight	243.73000
Flash Point	146.8ºC
Exact Mass	243.10300
PSA	32.70000
LogP	2.68960

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NX5980000

CHEMICAL NAME :: 7-Isoquinolinol, 1,2,3,4-tetrahydro-1,2-dimethyl-6-methoxy-, hydrochloride, (1R)-(-)-

CAS REGISTRY NUMBER :: 51713-80-5

LAST UPDATED :: 199012

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H17-N-O2.Cl-H

MOLECULAR WEIGHT :: 243.76

WISWESSER LINE NOTATION :: T66 CNT&J B1 C1 HO1 IQ &GH -1R(-)

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 17,134,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 17,134,1974