9-Methylstreptimidone

Modify Date: 2024-01-30 15:32:29

9-Methylstreptimidone structure	Common Name	9-Methylstreptimidone
	CAS Number	51867-94-8	Molecular Weight	307.38500
	Density	1.095g/cm3	Boiling Point	519.5ºC at 760mmHg
	Molecular Formula	C₁₇H₂₅NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	268ºC

Use of 9-Methylstreptimidone

Antibiotic TS 885 is a microbial metabolite that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro. 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.

Name	streptimidone, (+)-9-methyl
Synonym	More Synonyms

Density	1.095g/cm3
Boiling Point	519.5ºC at 760mmHg
Molecular Formula	C₁₇H₂₅NO₄
Molecular Weight	307.38500
Flash Point	268ºC
Exact Mass	307.17800
PSA	83.47000
LogP	2.23670
Index of Refraction	1.509

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM7510000

CHEMICAL NAME :: 2,6-Piperidinedione, 4-(2-hydroxy-5,7-dimethyl-4-oxo-6,8-decadiennyl)-

CAS REGISTRY NUMBER :: 51867-94-8

BEILSTEIN REFERENCE NO. :: 1545072

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C17-H25-N-O4

MOLECULAR WEIGHT :: 307.43

WISWESSER LINE NOTATION :: T6VMVTJ E1YQ1VY1&1UY1&1U2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,206,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 210 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,206,1974

HS Code	2925190090

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%