bPiDDB
Modify Date: 2024-02-17 09:23:03
bPiDDB structure
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Common Name | bPiDDB | ||
|---|---|---|---|---|
| CAS Number | 525596-66-1 | Molecular Weight | 514.38000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H38Br2N2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of bPiDDBbPiDDB is a potent nAChR antagonist. bPiDDB potently (IC50=2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs[1]. |
| Name | 1,1'-(1,12-Dodecanediyl)bis(3-methylpyridinium) dibromide |
|---|
| Description | bPiDDB is a potent nAChR antagonist. bPiDDB potently (IC50=2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs[1]. |
|---|---|
| Related Catalog | |
| In Vivo | bPiDDB (外周给药) 可抑制伏隔核中尼古丁诱发的多巴胺 (DA) 释放，降低大鼠尼古丁的成瘾性[1]。 bPiDDB 在外周给药后具有脑生物可利用性，并由血脑屏障胆碱转运体主动运输到中央室[1]。 |
| References |
| Molecular Formula | C24H38Br2N2 |
|---|---|
| Molecular Weight | 514.38000 |
| Exact Mass | 512.14000 |
| PSA | 7.76000 |