Tetrahydrocortisone
Tetrahydrocortisone structure
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Common Name | Tetrahydrocortisone | ||
|---|---|---|---|---|
| CAS Number | 53-05-4 | Molecular Weight | 364.47600 | |
| Density | 1.249g/cm3 | Boiling Point | 544.5ºC at 760mmHg | |
| Molecular Formula | C21H32O5 | Melting Point | 190°C | |
| MSDS | USA | Flash Point | 297.1ºC | |
Use of TetrahydrocortisoneTetrahydrocortisone is a stress-induced hormone. Tetrahydrocortisone is also a urinary metabolite of Cortisone derived from the reduction of Cortisone by 5-reductase[1]. |
Summary: Tetrahydro Cortisone, Chinese name is 四氢可的松, CAS number is 53-05-4, molecular formula is C21H32O5, molecular weight is 364.47600, melting point is 190°C, boiling point is 544.5°C, density is 1.249g/cm3. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Tetrahydro Cortisone |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Tetrahydrocortisone is a stress-induced hormone. Tetrahydrocortisone is also a urinary metabolite of Cortisone derived from the reduction of Cortisone by 5-reductase[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Thiam Chye TAN, et al. Characteristic metabolites in miscarriages. WO2018199849A1. |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.249g/cm3 |
|---|---|
| Boiling Point | 544.5ºC at 760mmHg |
| Melting Point | 190°C |
| Molecular Formula | C21H32O5 |
| Molecular Weight | 364.47600 |
| Flash Point | 297.1ºC |
| Exact Mass | 364.22500 |
| PSA | 94.83000 |
| LogP | 1.86150 |
| Index of Refraction | 1.569 |
| InChIKey | SYGWGHVTLUBCEM-ZIZPXRJBSA-N |
| SMILES | CC12CCC(O)CC1CCC1C2C(=O)CC2(C)C1CCC2(O)C(=O)CO |
| Storage condition | -20°C |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 0 | |
|---|---|
| DownStream 1 | |
CAS#:1482-51-5This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimo...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 1B1
External Id: CHEMBL3039488
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|
Name: Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimo...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 1B3
External Id: CHEMBL3039491
|
|
Name: Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening
Source: 11827
Target: Phosphogluconate dehydrogenase
External Id: 6PGD_Inhibitor_Screening_2015_09
|
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (3R,5R,8S,9S,10S,13S,14S,17R)-3,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the melting point of Tetrahydro Cortisone? |
| A: Melting point of Tetrahydro Cortisone is 190°C. |
| Q: What is the molecular weight of Tetrahydro Cortisone? |
| A: Molecular weight of Tetrahydro Cortisone is 364.47600. |
| Q: What is the English name of Tetrahydro Cortisone? |
| A: The English name of Tetrahydro Cortisone is Tetrahydro Cortisone. |
| Q: What are the downstream products of Tetrahydro Cortisone? |
| A: Related downstream products(CAS) of Tetrahydro Cortisone: 1482-51-5. |
| Q: What is the polar surface area (PSA) of Tetrahydro Cortisone? |
| A: Polar surface area (PSA) of Tetrahydro Cortisone is 94.83000. |
| Q: What is the boiling point of Tetrahydro Cortisone? |
| A: Boiling point of Tetrahydro Cortisone is 544.5ºC at 760mmHg. |
| Q: What English synonyms does Tetrahydro Cortisone have? |
| A: English synonyms of Tetrahydro Cortisone: (3R,5R,8S,9S,10S,13S,14S,17R)-3,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one. |
| Q: What is the LogP of Tetrahydro Cortisone? |
| A: LogP of Tetrahydro Cortisone is 1.86150. |
| Q: What is the molecular formula of Tetrahydro Cortisone? |
| A: Molecular formula of Tetrahydro Cortisone is C21H32O5. |
| Q: What is the InChIKey of Tetrahydro Cortisone? |
| A: InChIKey of Tetrahydro Cortisone is SYGWGHVTLUBCEM-ZIZPXRJBSA-N. |