5,12-Dihydroquinoxalino[2,3-b]quinoxaline

Modify Date: 2024-01-06 06:47:14

5,12-Dihydroquinoxalino[2,3-b]quinoxaline Structure
5,12-Dihydroquinoxalino[2,3-b]quinoxaline structure
Common Name 5,12-Dihydroquinoxalino[2,3-b]quinoxaline
CAS Number 531-46-4 Molecular Weight 234.256
Density 1.3±0.1 g/cm3 Boiling Point 477.5±33.0 °C at 760 mmHg
Molecular Formula C14H10N4 Melting Point N/A
MSDS N/A Flash Point 242.6±25.4 °C

 Use of 5,12-Dihydroquinoxalino[2,3-b]quinoxaline


Fluoflavine (ML-090) is a selective NOX1 inhibitor with an IC50 of 90 nM. Fluoflavine has >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50>10 μM). ML-090 has an IC50 of 360 nM in HEK293 cells[1].

 Names

Name fluoflavine
Synonym More Synonyms

  Biological Activity

Description Fluoflavine (ML-090) is a selective NOX1 inhibitor with an IC50 of 90 nM. Fluoflavine has >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50>10 μM). ML-090 has an IC50 of 360 nM in HEK293 cells[1].
Related Catalog
References

[1]. SJ Brown, et al. Probe Report for NOX1 Inhibitors.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 477.5±33.0 °C at 760 mmHg
Molecular Formula C14H10N4
Molecular Weight 234.256
Flash Point 242.6±25.4 °C
Exact Mass 234.090546
PSA 57.36000
LogP 2.93
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.711

 Safety Information

HS Code 2933990090

 Precursor & DownStream

Precursor  0

DownStream  2

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

5,12-Dihydroquinoxalino[2,3-b]quinoxaline
Quinoxalino[2,3-b]quinoxaline, 5,12-dihydro-
5,11-dihydro-5,6,11,12-tetraazanaphthacene
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