acridine-3,6-diamine dihydrochloride

Modify Date: 2024-01-03 11:04:33

acridine-3,6-diamine dihydrochloride Structure
acridine-3,6-diamine dihydrochloride structure
Common Name acridine-3,6-diamine dihydrochloride
CAS Number 531-73-7 Molecular Weight 282.17
Density N/A Boiling Point 506.9ºC at 760mmHg
Molecular Formula C13H13Cl2N3 Melting Point N/A
MSDS N/A Flash Point 292.9ºC

 Use of acridine-3,6-diamine dihydrochloride


Proflavine (3,6-Diaminoacridine) dihydrochloride, an acridine dye, is a DNA intercalating agent and Anti-microbial agent. Proflavine dihydrochloride behaves as a pore blocker for Kir3.2. Proflavine dihydrochloride is a potential lead compound for Kir3.2-associated neurological diseases[1][2][3].

 Names

Name 3,6-diaminoacridine dihydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 506.9ºC at 760mmHg
Molecular Formula C13H13Cl2N3
Molecular Weight 282.17
Flash Point 292.9ºC
Exact Mass 281.04900
PSA 64.93000
LogP 5.31880

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR8700000
CHEMICAL NAME :
Acridine, 3,6-diamino-, dihydrochloride
CAS REGISTRY NUMBER :
531-73-7
LAST UPDATED :
199409
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C13-H11-N3.2Cl-H
MOLECULAR WEIGHT :
282.19
WISWESSER LINE NOTATION :
T C666 BNJ EZ MZ &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Rodent - mouse Ascites tumor
DOSE/DURATION :
20 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Proflavine dihydrochloride
2,8-Diaminoacridinium chloride hydrochloride
EINECS 208-515-4
Acridine-3,6-diamine dihydrochloride
ACRIDINE,3,6-DIAMINO-,DIHYDROCHLORIDE
3,6-Diaminoacridinium chloride hydrochloride
proflavin.2HCl
3,6-Diaminoacridine dihydrochloride
acridine-3,6-diamine,dihydrochloride
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