L-Pinaverium bromide

Modify Date: 2024-01-04 12:24:34

L-Pinaverium bromide structure	Common Name	L-Pinaverium bromide
	CAS Number	53251-94-8	Molecular Weight	591.416
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₄₁Br₂NO₄	Melting Point	159-164ºC
	MSDS	N/A	Flash Point	N/A

Use of L-Pinaverium bromide

Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients[1].

Name	4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethyl-4-bicyclo[3.1.1]heptanyl)ethoxy]ethyl]morpholin-4-ium,bromide
Synonym	More Synonyms

Description	Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Others
Target	Calcium channel[1].
References	[1]. Dai Y, et al. Effect of pinaverium bromide on stress-induced colonic smooth muscle contractility disorder in rats. World J Gastroenterol. 2003 Mar;9(3):557-61.

Melting Point	159-164ºC
Molecular Formula	C₂₆H₄₁Br₂NO₄
Molecular Weight	591.416
Exact Mass	589.140198
PSA	36.92000
LogP	2.25510
Storage condition	-20°C Freezer

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QF2810000

CHEMICAL NAME :: Morpholinium, 4-(2-bromo-4,5-dimethoxy)benzyl-4-(2-(2-(6,6-dimethyl -2-norpinyl)ethoxy) ethyl)-, bromide

CAS REGISTRY NUMBER :: 53251-94-8

LAST UPDATED :: 199109

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C26-H41-Br-N-O4.Br

MOLECULAR WEIGHT :: 591.50

WISWESSER LINE NOTATION :: L46 ATJ A1 A1 E2O2- AT6K DOTJ A1R BE DO1 EO1 &E &24/47

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 504 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 40,133,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 37 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,182,1974

Precursor 2
CAS#:53207-00-4 2-Bromo-4,5-dim... CAS#:38284-47-8 (1S,2S,5S)-4-[2...
DownStream 0

4-(6-Bromoveratryl)-4-[2-[2-(6,6-dimethyl-2-norpinyl)ethoxy]ethyl]morpholinium Bromide

LAT 1717

Dicetel

EINECS 258-450-0

Pinaverium bromide

UNII-7SCF54H12J

Morpholinium, 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]-, bromide (1:1)

4-(2-Bromo-4,5-dimethoxybenzyl)-4-{2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl}morpholin-4-ium bromide

4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]morpholinium Bromide

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: L-Pinaverium bromide
Price: ￥328.0/1g
Purity: 95.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Pinaverium bromide
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Pinaverium bromide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Pinaverium bromide
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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L-Pinaverium bromide

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