1,2-bis(4-fluorophenyl)-2-hydroxyethanone

Modify Date: 2025-10-10 09:28:07

1,2-bis(4-fluorophenyl)-2-hydroxyethanone Structure
1,2-bis(4-fluorophenyl)-2-hydroxyethanone structure
Common Name 1,2-bis(4-fluorophenyl)-2-hydroxyethanone
CAS Number 53458-16-5 Molecular Weight 248.22500
Density 1.317 g/cm3 Boiling Point 376ºC at 760 mmHg
Molecular Formula C14H10F2O2 Melting Point N/A
MSDS N/A Flash Point 181.2ºC

 Names

Name 1,2-bis(4-fluorophenyl)-2-hydroxyethanone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.317 g/cm3
Boiling Point 376ºC at 760 mmHg
Molecular Formula C14H10F2O2
Molecular Weight 248.22500
Flash Point 181.2ºC
Exact Mass 248.06500
PSA 37.30000
LogP 2.88110
Index of Refraction 1.575
InChIKey VGZHWXAFILGMSR-UHFFFAOYSA-N
SMILES O=C(c1ccc(F)cc1)C(O)c1ccc(F)cc1

 Safety Information

HS Code 2914700090

 Synthetic Route

~86%

1,2-bis(4-fluorophenyl)-2-hydroxyethanone Structure

1,2-bis(4-fluor...

CAS#:53458-16-5

Literature: Lin, Wei; Hu, Ming-Hua; Feng, Xian; Fu, Lei; Cao, Cheng-Pao; Huang, Zhi-Bin; Shi, Da-Qing Tetrahedron Letters, 2014 , vol. 55, # 14 p. 2238 - 2242

~97%

1,2-bis(4-fluorophenyl)-2-hydroxyethanone Structure

1,2-bis(4-fluor...

CAS#:53458-16-5

Literature: Iwamoto, Ken-Ichi; Kimura, Hitomi; Oike, Masaaki; Sato, Masayuki Organic and Biomolecular Chemistry, 2008 , vol. 6, # 5 p. 912 - 915

~27%

1,2-bis(4-fluorophenyl)-2-hydroxyethanone Structure

1,2-bis(4-fluor...

CAS#:53458-16-5

Literature: Advanced Synthesis and Catalysis, , vol. 346, # 11 p. 1329 - 1334

~31%

1,2-bis(4-fluorophenyl)-2-hydroxyethanone Structure

1,2-bis(4-fluor...

CAS#:53458-16-5

Literature: Advanced Synthesis and Catalysis, , vol. 346, # 11 p. 1329 - 1334

~6%

1,2-bis(4-fluorophenyl)-2-hydroxyethanone Structure

1,2-bis(4-fluor...

CAS#:53458-16-5

Literature: Synthetic Communications, , vol. 44, # 2 p. 259 - 266

~%

1,2-bis(4-fluorophenyl)-2-hydroxyethanone Structure

1,2-bis(4-fluor...

CAS#:53458-16-5

Literature: Organic Letters, , vol. 1, # 7 p. 1119 - 1121

~%

1,2-bis(4-fluorophenyl)-2-hydroxyethanone Structure

1,2-bis(4-fluor...

CAS#:53458-16-5

Literature: Journal of Medicinal Chemistry, , vol. 36, # 23 p. 3658 - 3662

~%

1,2-bis(4-fluorophenyl)-2-hydroxyethanone Structure

1,2-bis(4-fluor...

CAS#:53458-16-5

Literature: Tetrahedron Letters, , vol. 33, # 17 p. 2283 - 2284

 Customs

HS Code 2914700090
Summary HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

 Synonyms

4,4'-difluorobenzoin
1,2-bis-(4-fluorophenyl)-2-hydroxyethan-1-one
EINECS 258-565-6
1,2-bis-[(4-fluoro)-phenyl]-2-hydroxyethanone
2-hydroxy-1,2-bis(4-fluorophenyl)ethanone
4,4'-fluorobenzoin
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