Diperodon (hydrochloride)

Modify Date: 2024-01-14 10:42:17

Diperodon (hydrochloride) structure	Common Name	Diperodon (hydrochloride)
	CAS Number	537-12-2	Molecular Weight	433.92800
	Density	N/A	Boiling Point	502ºC at 760mmHg
	Molecular Formula	C₂₂H₂₈ClN₃O₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	257.4ºC
	Symbol	GHS07	Signal Word	Warning

Use of Diperodon (hydrochloride)

Diperodon is a local anaesthetics, by the action of hydrolazes in blood serum is decomposed.

Name	[2-(phenylcarbamoyloxy)-3-piperidin-1-ylpropyl] N-phenylcarbamate,hydrochloride
Synonym	More Synonyms

Description	Diperodon is a local anaesthetics, by the action of hydrolazes in blood serum is decomposed.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Cizmárik J, et al. Study of local anaesthetics. Part 133. Determination of diperodon in blood serum in vitro by the HPLC method. Acta Pol Pharm. 1996 May-Jun;53(3):167-169.

Boiling Point	502ºC at 760mmHg
Molecular Formula	C₂₂H₂₈ClN₃O₄
Molecular Weight	433.92800
Flash Point	257.4ºC
Exact Mass	433.17700
PSA	79.90000
LogP	5.22420

Diperodon (hydrochloride) MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TZ1101000

CHEMICAL NAME :: 1,2-Propanediol, 3-piperidino-, dicarbanilate, hydrochloride

CAS REGISTRY NUMBER :: 537-12-2

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C22-H27-N3-O4.Cl-H

MOLECULAR WEIGHT :: 433.98

WISWESSER LINE NOTATION :: T6NTJ A1YOVMR&&1OVMR &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 890 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - local anesthetic

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 48,398,1959

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,255,1933

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - general anesthetic Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,255,1933

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,255,1933

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	26-37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TZ1101000
HS Code	2933399090

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Study of local anaesthetics. Part 133. Determination of diperodon in blood serum in vitro by the HPLC method.

Acta Pol. Pharm. 53(3) , 167-9, (1996)

A local anaesthetics diperodon by the action of hydrolazes in blood serum is decomposed. A method for its determination in blood serum in vitro has been worked out. It was found that during the first ...

[HPLC determination of diperodon enantiomers in blood serum by using teicoplanin chiral stationary phase].

Ceska. Slov. Farm. 53(5) , 225-7, (2004)

The chiral stationary phase on the base of teicoplanin and the polar-organic mobile phase methanol/acetonitrile/acetic acid/triethylamine 45/55/0.3/0.2 was used for the separation of diperodon enantio...

In vitro study of enzymatic hydrolysis of diperodon enantiomers in blood serum by two-dimensional LC.

J. Pharm. Biomed. Anal. 30(3) , 875-80, (2002)

An on-line coupled HPLC system is described for the determination of the enantiomers of diperodon in blood serum. The method involves three steps: (i) off-line preconcentration and clean-up, (ii) sepa...

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Diperodon HCl
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,2-Propanediol,3-(1-piperidinyl)-, 1,2-bis(N-phenylcarbamate), hydrochloride (1:1)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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