Mefluidide

Modify Date: 2024-01-03 08:24:23

Mefluidide Structure
Mefluidide structure
Common Name Mefluidide
CAS Number 53780-34-0 Molecular Weight 310.29
Density 1.464g/cm3 Boiling Point N/A
Molecular Formula C11H13F3N2O3S Melting Point 183-185°
MSDS Chinese USA Flash Point N/A

 Use of Mefluidide


Mefluidide is a potent inhibitor of KCS6, CER60 and CER1 enzymes and can be used in herbicide research[1].

 Names

Name mefluidide
Synonym More Synonyms

 Mefluidide Biological Activity

Description Mefluidide is a potent inhibitor of KCS6, CER60 and CER1 enzymes and can be used in herbicide research[1].
Related Catalog
References

[1]. Tresch S, et al. Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases. Phytochemistry. 2012 Apr;76:162-71.  

 Chemical & Physical Properties

Density 1.464g/cm3
Melting Point 183-185°
Molecular Formula C11H13F3N2O3S
Molecular Weight 310.29
Exact Mass 310.06000
PSA 83.65000
LogP 3.75010
Index of Refraction 1.539

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AE2460000
CHEMICAL NAME :
Acetanilide, 2',4'-dimethyl-5-((trifluoromethyl)sulfonamido)-
CAS REGISTRY NUMBER :
53780-34-0
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C11-H13-F3-N2-O3-S
MOLECULAR WEIGHT :
310.32
WISWESSER LINE NOTATION :
FXFFSWMR B1 D1 EMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision Volume(issue)/page/year: 3,66,1976/1977
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>8500 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A256,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1920 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,545,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A256,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>4620 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A256,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>4640 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,545,1991 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

 Safety Information

RIDADR UN3077 (solid); UN3082 (liquid)
RTECS AE2460000
HS Code 2935009015

 Synthetic Route

~86%

Detail
Literature: Gmelin Handbook: F: PerFHalOrg.SVol.3, 6.2.3.4, page 152 - 186

 Customs

HS Code 2935009015
Summary 2935009015 n-(2,4-dimethyl-5-(trifluoromethylsulfonamido)phenyl)acetamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%

 Articles6

More Articles
Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases.

Phytochemistry 76 , 162-71, (2012)

The trifluoromethanesulphonanilides mefluidide and perfluidone are used in agriculture as plant growth regulators and herbicides. Despite the fact that mefluidide and perfluidone have been investigate...

Mefluidide treatment of tall fescue pastures: intake and animal performance.

J. Anim. Sci. 68(10) , 3399-405, (1990)

Twelve Hereford heifers were used in a grazing experiment to determine intake and digestibility of tall fescue forage treated with the plant growth regulator mefluidide. Additionally, steer and heifer...

Fate of the plant growth regulator mefluidide [N-[2,4-dimethyl-5-[[(trifluoromethyl)sulfonyl]amino]phenyl]acetamide] in a cow and sheep.

J. Agric. Food Chem. 28(6) , 1286-8, (1980)

 Synonyms

N-[2,4-dimethyl-5-(trifluoromethylsulfonylamino)phenyl]acetamide
2',4'-dimethyl-5'-trifluoromethylsulfonylaminoacetanilide
N-[2,4-dimethyl-5-[[(trifluoromethyl)sulfonyl]amino]phenyl]acetamide
Embark
Embark plant growth regulator
5’-(1,1,1-trifluoromethanesulfonamido)acet-2’,4’-xylidide
EINECS 258-767-4
5-Acetamido-2,4-dimethyltrifluoromethanesulfonanilide
Embark 2S
N-[2,4-dimethyl-5-(1,1,1-trifluoromethanesulfonamido)phenyl]acetamide
Vistar herbicide
VEL 3973
Vistar
Trim-Cut
MEFLUIDIDE