4-(2H4)Pyridinecarboxylic acid
Modify Date: 2024-01-03 11:37:44
4-(2H4)Pyridinecarboxylic acid structure
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Common Name | 4-(2H4)Pyridinecarboxylic acid | ||
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| CAS Number | 53907-55-4 | Molecular Weight | 127.134 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 396.0±15.0 °C at 760 mmHg | |
| Molecular Formula | C6HD4NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 193.3±20.4 °C | |
Use of 4-(2H4)Pyridinecarboxylic acidIsonicotinic acid-d4 is the deuterium labeled Isonicotinic acid[1]. Isonicotinic acid is a metabolite of Isoniazid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the Isoniazid to Isonicotinic acid biotransformation also to be catalyzed by cytochrome P450 (CYP) enzymes, e.g., CYP2C[2]. |
| Name | isonicotinic-d4 acid |
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| Synonym | More Synonyms |
| Description | Isonicotinic acid-d4 is the deuterium labeled Isonicotinic acid[1]. Isonicotinic acid is a metabolite of Isoniazid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the Isoniazid to Isonicotinic acid biotransformation also to be catalyzed by cytochrome P450 (CYP) enzymes, e.g., CYP2C[2]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 396.0±15.0 °C at 760 mmHg |
| Molecular Formula | C6HD4NO2 |
| Molecular Weight | 127.134 |
| Flash Point | 193.3±20.4 °C |
| Exact Mass | 127.057137 |
| PSA | 50.19000 |
| LogP | 0.54 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.571 |
| (H)Pyridine-4-carboxylic acid |
| 4-(H)Pyridinecarboxylic acid |
| 4-Pyridine-d-carboxylic acid |