Estr-4-en-3-one,17-[[[(2-chloroethyl)nitrosoamino]carbonyl]oxy]-, (17b)- (9CI)

Modify Date: 2024-04-01 22:36:51

Estr-4-en-3-one,17-[[[(2-chloroethyl)nitrosoamino]carbonyl]oxy]-, (17b)- (9CI) structure	Common Name	Estr-4-en-3-one,17-[[[(2-chloroethyl)nitrosoamino]carbonyl]oxy]-, (17b)- (9CI)
	CAS Number	54025-36-4	Molecular Weight	408.91900
	Density	1.43g/cm3	Boiling Point	529.4ºC at 760mmHg
	Molecular Formula	C₂₁H₂₉ClN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	274ºC

Name	Estr-4-en-3-one, 17-[[[(2-chloroethyl)nitrosoamino]carbonyl]oxy]-, (17.β.)
Synonym	More Synonyms

Density	1.43g/cm3
Boiling Point	529.4ºC at 760mmHg
Molecular Formula	C₂₁H₂₉ClN₂O₄
Molecular Weight	408.91900
Flash Point	274ºC
Exact Mass	408.18200
PSA	76.04000
LogP	4.85560
Index of Refraction	1.661

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KG7962400

CHEMICAL NAME :: Estr-4-en-3-one, 17-((((2-chloroethyl)nitrosoamino)carbonyl)oxy)-, (17-beta)-

CAS REGISTRY NUMBER :: 54025-36-4

LAST UPDATED :: 198602

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C21-H29-Cl-N2-O4

MOLECULAR WEIGHT :: 408.97

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2190 mg/kg

TOXIC EFFECTS :: Gastrointestinal - gastritis Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 155 mg/kg

TOXIC EFFECTS :: Gastrointestinal - gastritis Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - gastritis Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981

TYPE OF TEST :: LD10 - Lethal Dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1630 mg/kg

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from stomach Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 98 mg/kg

TOXIC EFFECTS :: Gastrointestinal - peritonitis Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - gastritis Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981

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