3,4-Dimethoxychalcone

Modify Date: 2025-08-26 17:10:54

3,4-Dimethoxychalcone Structure
3,4-Dimethoxychalcone structure
Common Name 3,4-Dimethoxychalcone
CAS Number 5416-71-7 Molecular Weight 268.31
Density 1.128g/cm3 Boiling Point 421.8ºC at 760mmHg
Molecular Formula C17H16O3 Melting Point 88ºC
MSDS N/A Flash Point 200.7ºC

 Use of 3,4-Dimethoxychalcone


3,4-Dimethoxychalcone is a Caloric restriction mimetics (CRMs). 3,4-Dimethoxychalcone induces the deacetylation of cytoplasmic proteins and stimulates autophagy flux. 3,4-Dimethoxychalcone can be used for cardiac and cancer diseases research[1].

 Names

Name 3,4-dimethoxychalcone
Synonym More Synonyms

 3,4-Dimethoxychalcone Biological Activity

Description 3,4-Dimethoxychalcone is a Caloric restriction mimetics (CRMs). 3,4-Dimethoxychalcone induces the deacetylation of cytoplasmic proteins and stimulates autophagy flux. 3,4-Dimethoxychalcone can be used for cardiac and cancer diseases research[1].
Related Catalog
References

[1]. Okolo EN, et al. New chalcone derivatives as potential antimicrobial and antioxidant agent. Sci Rep. 2021 Nov 5;11(1):21781.  

[2]. Chen G, et al. 3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB. EMBO Mol Med. 2019 Nov 7;11(11):e10469.  

 Chemical & Physical Properties

Density 1.128g/cm3
Boiling Point 421.8ºC at 760mmHg
Melting Point 88ºC
Molecular Formula C17H16O3
Molecular Weight 268.31
Flash Point 200.7ºC
Exact Mass 268.11000
PSA 35.53000
LogP 3.59990

 Synonyms

1-phenyl-3-(3,4-dimethoxyphenyl)-2-propen-1-one
3,4-dimethoxybenzylideneacetophenone
(E)-3-(3,4-DIMETHOXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE
3-(3,4-dimethoxy-phenyl)-1-propenone
3,4-Dimethoxy-chalkon
DIMETHOXYCHALCONE,3,4
3,4-dimethoxy-chalcone
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