BMS-433771 dihydrochloride hydrate
Modify Date: 2024-01-12 10:27:32
BMS-433771 dihydrochloride hydrate structure
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Common Name | BMS-433771 dihydrochloride hydrate | ||
|---|---|---|---|---|
| CAS Number | 543700-67-0 | Molecular Weight | 468.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H27Cl2N5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BMS-433771 dihydrochloride hydrateBMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease[1][2]. |
| Name | BMS-433771 dihydrochloride hydrate |
|---|
| Description | BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease[1][2]. |
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| Related Catalog | |
| Target |
EC50: 20 nM (RSV)[1] |
| In Vitro | BMS-433771 dihydrochloride hydrate 对 A 组和 B 组 RSV 均具有抑制作用，平均 EC50 为 20 nM[1]。 BMS-433771 dihydrochloride hydrate 可抑制病毒 F 蛋白诱导的膜融合[1]。 |
| In Vivo | BMS-433771 dihydrochloride hydrate (口服；1-200 mg/kg；每天 1 或 2 次，共 4 天) 通过口服给药显示出预防效果，但两种啮齿动物模型之间具有相当大的药效学差异[2] . |
| References |
| Molecular Formula | C21H27Cl2N5O3 |
|---|---|
| Molecular Weight | 468.38 |