NSC 204855

Modify Date: 2024-04-12 09:39:27

NSC 204855 Structure
NSC 204855 structure
Common Name NSC 204855
CAS Number 54526-94-2 Molecular Weight 588.55700
Density 1.52g/cm3 Boiling Point 801.2ºC at 760 mmHg
Molecular Formula C29H32O13 Melting Point N/A
MSDS N/A Flash Point 262.3ºC

 Use of NSC 204855


Steffimycin B is an anthracycline bacterial metabolite. It binds to DNA, preferentially intercalating at sites containing cytosine and guanine. Steffimycin B is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells. It is active against M. tuberculosis, B. cereus, and P. falciparum.

 Names

Name 2,5,7-trihydroxy-4-(4-hydroxy-3,5-dimethoxy-6-methyloxan-2-yl)oxy-3,9-dimethoxy-2-methyl-3,4-dihydrotetracene-1,6,11-trione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.52g/cm3
Boiling Point 801.2ºC at 760 mmHg
Molecular Formula C29H32O13
Molecular Weight 588.55700
Flash Point 262.3ºC
Exact Mass 588.18400
PSA 187.51000
LogP 1.03750
Index of Refraction 1.647

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QI9450000
CHEMICAL NAME :
1,6,11(2H)-Naphthacenetrione, 4-((6-deoxy-2,4-di-O-methyl-alpha-L-mannopyranosyl)ox y)-3,4- dihydro-2,5,7-trihydroxy-3,9-dimethoxy-2-methyl-
CAS REGISTRY NUMBER :
54526-94-2
LAST UPDATED :
199409
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C29-H32-O13
MOLECULAR WEIGHT :
588.61
WISWESSER LINE NOTATION :
L E6 C666 BV FV MVT&&&J GQ G1 HO1 KQ OQ QO1 IO- BT6OTJ CO1 DO1 EQ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
5100 nmol/L
REFERENCE :
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 25,59,1979

 Synonyms

Steffimycin B
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