4-(4-bromophenyl)-3-[(2-methyl-1H-indol-3-yl)methyl]-1H-1,2,4-triazole-5-thione

Modify Date: 2023-10-16 18:14:03

4-(4-bromophenyl)-3-[(2-methyl-1H-indol-3-yl)methyl]-1H-1,2,4-triazole-5-thione Structure
4-(4-bromophenyl)-3-[(2-methyl-1H-indol-3-yl)methyl]-1H-1,2,4-triazole-5-thione structure
Common Name 4-(4-bromophenyl)-3-[(2-methyl-1H-indol-3-yl)methyl]-1H-1,2,4-triazole-5-thione
CAS Number 54649-04-6 Molecular Weight 399.30800
Density 1.57g/cm3 Boiling Point 561.7ºC at 760 mmHg
Molecular Formula C18H15BrN4S Melting Point N/A
MSDS N/A Flash Point 293.5ºC

 Names

Name 4-(4-bromophenyl)-3-[(2-methyl-1H-indol-3-yl)methyl]-1H-1,2,4-triazole-5-thione

 Chemical & Physical Properties

Density 1.57g/cm3
Boiling Point 561.7ºC at 760 mmHg
Molecular Formula C18H15BrN4S
Molecular Weight 399.30800
Flash Point 293.5ºC
Exact Mass 398.02000
PSA 85.30000
LogP 4.69900
Index of Refraction 1.748

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XZ5359010
CHEMICAL NAME :
3H-1,2,4-Triazole-3-thione, 2,4-dihydro-4-(4-bromophenyl)-5-((2-methyl-1H-indol-3 -yl) methyl)-
CAS REGISTRY NUMBER :
54649-04-6
LAST UPDATED :
198512
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C18-H15-Br-N4-S
MOLECULAR WEIGHT :
399.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
CNJPAZ Canadian Journal of Pharmaceutical Sciences. (Toronto, Ont., Canada) V.1-16, 1966-81. Discontinued. Volume(issue)/page/year: 9,108,1974
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