(1,3)Benzodioxolo(5,6-c)phenanthridin-13(12H)-one, 2,3-dimethoxy-12-methyl

Modify Date: 2025-08-24 12:09:47

(1,3)Benzodioxolo(5,6-c)phenanthridin-13(12H)-one, 2,3-dimethoxy-12-methyl structure	Common Name	(1,3)Benzodioxolo(5,6-c)phenanthridin-13(12H)-one, 2,3-dimethoxy-12-methyl
	CAS Number	548-31-2	Molecular Weight	363.36
	Density	1.361g/cm3	Boiling Point	614.2ºC at 760 mmHg
	Molecular Formula	C₂₁H₁₇NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	325.3ºC

Use of (1,3)Benzodioxolo(5,6-c)phenanthridin-13(12H)-one, 2,3-dimethoxy-12-methyl

Oxynitidine is an HBV inhibitor (ID50=30.8 µg/mL), which can effectively inhibit the DNA replication activity of HBV. Oxynitidine can be used in the study of viral infections[1].

Name	2,3-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-13-one
Synonym	More Synonyms

Description	Oxynitidine is an HBV inhibitor (ID50=30.8 µg/mL), which can effectively inhibit the DNA replication activity of HBV. Oxynitidine can be used in the study of viral infections[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV
References	[1]. Chin-Teng Chang, et al. Coumarins and anti-HBV constituents from Zanthoxylum schinifolium.

Density	1.361g/cm3
Boiling Point	614.2ºC at 760 mmHg
Molecular Formula	C₂₁H₁₇NO₅
Molecular Weight	363.36
Flash Point	325.3ºC
Exact Mass	363.11100
PSA	58.92000
LogP	3.59080
Index of Refraction	1.668
InChIKey	TVYBYUSEIMYSFA-UHFFFAOYSA-N
SMILES	COc1cc2c(=O)n(C)c3c4cc5c(cc4ccc3c2cc1OC)OCO5

Precursor 4
CAS#:688006-40-8 3-[6-(2-hydroxy... CAS#:1207666-60-1 2-(3-(benzo[d][... CAS#:690636-73-8 (E/Z)-6,7-dimet... CAS#:14382-91-3 2-hydroxy-4,5-d...
DownStream 4
CAS#:13063-04-2 Nitidine chloride CAS#:13063-06-4 [1,3]Benzodioxo... CAS#:114253-63-3 2,3,8,9-tetrame... CAS#:41349-35-3 (1,3)Benzodioxo...

Name: Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay
Source: ChEMBL
Target: DU-145
External Id: CHEMBL4364617

Name: Growth inhibition of human HCT116 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: HCT-116
External Id: CHEMBL4158476

Name: Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
Source: ChEMBL
Target: MCF7
External Id: CHEMBL4364616

Name: Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay
Source: ChEMBL
Target: CCRF-CEM
External Id: CHEMBL4158477

Name: Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay
Source: ChEMBL
Target: HCT-116
External Id: CHEMBL4364615

Name: Growth inhibition of human DU145 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: DU-145
External Id: CHEMBL4158478

Name: In vivo antitumor activity against mouse P388 cells at 30 to 50 mg/kg, ip relative to...
Source: ChEMBL
Target: P388
External Id: CHEMBL1021752

Name: Inhibition of recombinant TOP1 (unknown origin) using 3'-[32P]-labeled 117 bp DNA oli...
Source: ChEMBL
Target: DNA topoisomerase 1
External Id: CHEMBL4364613

Name: Binding affinity to F10T dsDNA (unknown origin) assessed as change in melting tempera...
Source: ChEMBL
Target: dsDNA
External Id: CHEMBL4158472

Name: Growth inhibition of human A549 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: A549
External Id: CHEMBL4158479

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6-oxynitidine

OXYNITIDINE

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(1,3)Benzodioxolo(5,6-c)phenanthridin-13(12H)-one, 2,3-dimethoxy-12-methyl

Use of (1,3)Benzodioxolo(5,6-c)phenanthridin-13(12H)-one, 2,3-dimethoxy-12-methyl

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.