2-methoxy-7-nitro-10H-acridin-9-one

Modify Date: 2025-08-26 19:26:01

2-methoxy-7-nitro-10H-acridin-9-one Structure
2-methoxy-7-nitro-10H-acridin-9-one structure
Common Name 2-methoxy-7-nitro-10H-acridin-9-one
CAS Number 5486-12-4 Molecular Weight 270.24000
Density 1.389g/cm3 Boiling Point 489.8ºC at 760mmHg
Molecular Formula C14H10N2O4 Melting Point N/A
MSDS N/A Flash Point 250ºC

 Names

Name 2-methoxy-7-nitro-10H-acridin-9-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.389g/cm3
Boiling Point 489.8ºC at 760mmHg
Molecular Formula C14H10N2O4
Molecular Weight 270.24000
Flash Point 250ºC
Exact Mass 270.06400
PSA 87.91000
LogP 3.12130
Index of Refraction 1.645
InChIKey GHDTZAUUYUVUKM-UHFFFAOYSA-N
SMILES COC1=CC2=C(C=C1)NC3=C(C2=O)C=C(C=C3)[N+](=O)[O-]

 Synthetic Route

~64%

2-methoxy-7-nitro-10H-acridin-9-one Structure

2-methoxy-7-nit...

CAS#:5486-12-4

Literature: Liu, Yungen; Wei, Jinhu; Che, Chi-Ming Chemical Communications, 2010 , vol. 46, # 37 p. 6926 - 6928

~87%

2-methoxy-7-nitro-10H-acridin-9-one Structure

2-methoxy-7-nit...

CAS#:5486-12-4

Literature: Shakhidoyatov; Samarov; Mukarramov; Levkovich; Abdullaev; Tashkhodzhaev; Barakat, Yasser; Urakov Chemistry of Natural Compounds, 2007 , vol. 43, # 4 p. 441 - 449

~%

2-methoxy-7-nitro-10H-acridin-9-one Structure

2-methoxy-7-nit...

CAS#:5486-12-4

Literature: Paterson, Thomas McC.; Smalley, Robert K.; Suschitzky, Hans; Barker, Alan J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 633 - 638

~%

2-methoxy-7-nitro-10H-acridin-9-one Structure

2-methoxy-7-nit...

CAS#:5486-12-4

Literature: Paterson, Thomas McC.; Smalley, Robert K.; Suschitzky, Hans; Barker, Alan J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 633 - 638

~%

2-methoxy-7-nitro-10H-acridin-9-one Structure

2-methoxy-7-nit...

CAS#:5486-12-4

Literature: Paterson, Thomas McC.; Smalley, Robert K.; Suschitzky, Hans; Barker, Alan J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 633 - 638

~%

2-methoxy-7-nitro-10H-acridin-9-one Structure

2-methoxy-7-nit...

CAS#:5486-12-4

Literature: Paterson, Thomas McC.; Smalley, Robert K.; Suschitzky, Hans; Barker, Alan J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 633 - 638

 2-methoxy-7-nitro-10H-acridin-9-oneBioassay

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Name: qHTS screening for TAG (triacylglycerol) accumulators in algae
Source: 11812
Target: N/A
External Id: FATTTLab-Algae-Lipid
Name: Selectivity ratio of IC50 for human recombinant cathepsin L to IC50 for human recombi...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2043891
Name: GPR151 activator identification: cell-based high-throughput counter-screen assay
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Glucose-dependent insulinotropic receptor; AltName: Full=G-protein coupled receptor 119
External Id: GPR119_PHUNTER_AG_LUMI_1536_3X%ACT CSRUN1
Name: GPR151 activator identification: cell-based high-throughput confirmation assay
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_3X%ACT CRUN1
Name: Alphascreen assay for small molecules abrogating mHTT-CaM Interaction
Source: 24983
Target: Huntingtin
External Id: KUHTS-Muma KU-CaM-Htt INH-01
Name: Inhibition of human recombinant cathepsin L expressed in Pichia pastoris using Z-Phe-...
Source: ChEMBL
Target: Procathepsin L
External Id: CHEMBL2043889
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: Inhibition of human recombinant cathepsin V expressed in Pichia pastoris using Z-Phe-...
Source: ChEMBL
Target: Cathepsin L2
External Id: CHEMBL2043890
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
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 Synonyms

2-methoxy-7-nitroacridin-9(10H)-one
5,5a,6,7,8,9-Hexahydro-pyrido<2,1-b>chinazolin-11-on
5,5a,6,7,8,9-hexahydropyrido[2,1-b]quinazolin-11-one
11-Oxo-5,5a,6,7,8,9-hexahydro-11H-pyrido<chinazolin
2,3-tetramethylene-1,2,3,4-tetrahydroquinazol-4-one
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