Prostaglandin F2α 1,15-lactone (PGF2α 1,15-lactone)

Modify Date: 2024-01-13 19:12:55

Prostaglandin F2α 1,15-lactone (PGF2α 1,15-lactone) Structure
Prostaglandin F2α 1,15-lactone (PGF2α 1,15-lactone) structure
Common Name Prostaglandin F2α 1,15-lactone (PGF2α 1,15-lactone)
CAS Number 55314-49-3 Molecular Weight 336.466
Density 1.1±0.1 g/cm3 Boiling Point 524.1±50.0 °C at 760 mmHg
Molecular Formula C20H32O4 Melting Point N/A
MSDS N/A Flash Point 180.9±23.6 °C

 Use of Prostaglandin F2α 1,15-lactone (PGF2α 1,15-lactone)


PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α.

 Names

Name 9alpha, 11alpha, 15s-trihydroxy-prosta-5z, 13e-dien-1-oic acid, 1,15-lactone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 524.1±50.0 °C at 760 mmHg
Molecular Formula C20H32O4
Molecular Weight 336.466
Flash Point 180.9±23.6 °C
Exact Mass 336.230072
PSA 66.76000
LogP 3.09
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.503

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UK8020600
CHEMICAL NAME :
Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, lambda-lactone, (5Z,9-alpha,11-alpha, 13E,15S)-
CAS REGISTRY NUMBER :
55314-49-3
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H32-O4
MOLECULAR WEIGHT :
336.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
DOSE :
4 mg/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 14,477,1977
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
800 ug/kg
SEX/DURATION :
female 4 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1089,1983

 Precursor & DownStream

Precursor  1

DownStream  1

 Synonyms

pgf2-alpha1,15-lactone
Prosta-5,13-dien-1-one, 1,15-epoxy-9,11-dihydroxy-, (5Z,9α,11α,13E,15S)-
(5Z,9α,11α,13E,15S)-9,11-Dihydroxy-1,15-epoxyprosta-5,13-dien-1-one
13e,15s)-1-alph
PROSTAGLANDIN F2ALPHA 1,15-LACTONE
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