Arsonic acid,As-[4-[(2-amino-2-oxoethyl)amino]phenyl]-, sodium salt (1:1)

Modify Date: 2025-08-25 15:54:26

Arsonic acid,As-[4-[(2-amino-2-oxoethyl)amino]phenyl]-, sodium salt (1:1) structure	Common Name	Arsonic acid,As-[4-[(2-amino-2-oxoethyl)amino]phenyl]-, sodium salt (1:1)
	CAS Number	554-72-3	Molecular Weight	296.08700
	Density	N/A	Boiling Point	687ºC at 760mmHg
	Molecular Formula	C₈H₁₀AsN₂NaO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	369.3ºC

Name	tryparsamide
Synonym	More Synonyms

Boiling Point	687ºC at 760mmHg
Molecular Formula	C₈H₁₀AsN₂NaO₄
Molecular Weight	296.08700
Flash Point	369.3ºC
Exact Mass	295.97500
PSA	115.48000
InChIKey	UEYIAABRKWHXJV-UHFFFAOYSA-M
SMILES	NC(=O)CNc1ccc([As](=O)([O-])O)cc1.[Na+]

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CF9480000

CHEMICAL NAME :: Arsanilic acid, N-(carbamoylmethyl)-, monosodium salt

CAS REGISTRY NUMBER :: 554-72-3

LAST UPDATED :: 198809

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C8-H10-As-N2-O4.Na

MOLECULAR WEIGHT :: 296.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 68,944,1946

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 2,28,1947

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 29,125,1931

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 29,125,1931

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 23,107,1924

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 29,125,1931

Name: Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum act...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3137722

Name: Highest frequency of moderate liver toxicity observed during clinical trials, express...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3137723

Name: Acute liver toxicity defined via clinical observations and clear clinical-chemistry r...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137724

Name: Highest frequency of acute liver toxicity observed during clinical trials, expressed ...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3137725

Name: Cytolytic liver toxicity, either proven histopathologically or where the ratio of max...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137726

Name: Choleostatic liver toxicity, either proven histopathologically or where the ratio of ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137727

Name: Severe hepatitis, defined as possibly life-threatening liver failure or through clini...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137728

Name: Chronic liver disease either proven histopathologically, or through a chonic elevatio...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137729

Name: Cirrhosis, proven histopathologically. Value is number of references indexed. [column...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3137730

Name: Granulomatous liver disease, proven histopathologically. Value is number of reference...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3137731

Total 19, Current Page 1 of 2

Monosodium N-(carbamoylmethyl)arsanilate

Trypothane

(4-(2-AMINO-2-OXOETHYL)AMINO)-PHENYL)ARSONICACID

Tryponersyl

Tryparsone

Novatoxyl

Glyphenarsine

Monosodium N-phenylglycinamide-p-arsonate

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Arsonic acid,As-[4-[(2-amino-2-oxoethyl)amino]phenyl]-, sodium salt (1:1)

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.