Teclozan

Modify Date: 2024-01-09 08:19:49

Teclozan Structure
Teclozan structure
 Common Name Teclozan
CAS Number 5560-78-1 Molecular Weight 502.25900
Density 1.294g/cm3 Boiling Point 585.8ºC at 760mmHg
Molecular Formula C20H28Cl4N2O4 Melting Point N/A
MSDS N/A Flash Point 308.1ºC

 Use of Teclozan


Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections[1][2].

 Names

Name 2,2-dichloro-N-[[4-[[(2,2-dichloroacetyl)-(2-ethoxyethyl)amino]methyl]phenyl]methyl]-N-(2-ethoxyethyl)acetamide
Synonym More Synonyms

 Teclozan Biological Activity

Description Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections[1][2].
Related Catalog
References

[1]. Gonzales MLM, et al. Antiamoebic drugs for treating amoebic colitis. Cochrane Database Syst Rev. 2019;1(1):CD006085. Published 2019 Jan 9.

[2]. Díaz, V. M. M. . Pharmacological Treatment of Giardiasis. In: Rodriguez-Morales, A. J. , editor. Current Topics in Giardiasis [Internet]. London: IntechOpen; 2017.

 Chemical & Physical Properties

Density 1.294g/cm3
Boiling Point 585.8ºC at 760mmHg
Molecular Formula C20H28Cl4N2O4
Molecular Weight 502.25900
Flash Point 308.1ºC
Exact Mass 500.08000
PSA 59.08000
LogP 4.02420
Index of Refraction 1.541

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AC7720000
CHEMICAL NAME :
Acetamide, N,N'-(1,4-phenylenebis(methylene))bis(2,2-dichloro-N- (2-ethoxyethyl)-
CAS REGISTRY NUMBER :
5560-78-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H28-Cl4-N2-O4
MOLECULAR WEIGHT :
502.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>8 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AJTHAB American Journal of Tropical Medicine and Hygiene. (Allen Press, 1041 New Hampshire St., Lawrence, KS 66044) V.1- 1952- Volume(issue)/page/year: 10,503,1961

 Synonyms

TECLOZAN
EINECS 226-934-0
Teclosan
1,4-Bis-<N-dichloracetyl-N-(2-ethoxy-ethyl)-aminomethyl>-benzol
Teclozanum [INN-Latin]
Falmonox
Teclosine
Teclozine
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Chemsrc provides Teclozan(CAS#:5560-78-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Teclozan are included as well.>> amp version: Teclozan

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