(Tyr8)-Substance P

Modify Date: 2025-08-27 12:12:54

(Tyr8)-Substance P structure	Common Name	(Tyr8)-Substance P
	CAS Number	55614-10-3	Molecular Weight	1363.63000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₃H₉₈N₁₈O₁₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Tyr8)-Substance P

[Tyr8]-Substance P is an active peptide. [Tyr8]-Substance P can be used for the research of various biochemical[1].

Name	arg-pro-lys-pro-gln-gln-phe-tyr-gly-leu-met-nh2
Synonym	More Synonyms

Description	[Tyr8]-Substance P is an active peptide. [Tyr8]-Substance P can be used for the research of various biochemical[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	[Tyr8]-Substance P at a very high dosage released LH and FSH in vitro[1].
In Vivo	[Tyr8]-Substance P shows the activity in contraction of the isolated guinea pig ileum and decrease in systemic blood pressure of dogs[1].
References	[1]. Fisher, et al. Hypothalamic hormones. 71. Synthesis and some biological activities of the tyrosine-8 analog of substance P. Journal of Medicinal Chemistry.Volume: 19. Issue: 2. Pages: 325-8. Journal; Article. 1976.

Molecular Formula	C₆₃H₉₈N₁₈O₁₄S
Molecular Weight	1363.63000
Exact Mass	1362.72000
PSA	562.16000
LogP	3.89970
InChIKey	MSKLWPIJUANGPO-CUZNLEPHSA-N
SMILES	CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)C1CCCN1C(=O)C(N)CCCN=C(N)N)C(N)=O

Name: Effect on thyrotropin hormone release in Sprague-Dawley rat pituitary gland at 100 ug...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3283824

Name: Effect on prolactin release in Sprague-Dawley rat pituitary gland at 100 ug/ml by rad...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3283823

Name: Retardation factor of the compound using CHCl3-MeOH-concentrated NH4OH at ratio of 60...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3283826

Name: Retardation factor of the compound using EtOAc-Pyr-HOAc-H2O at ratio of 5:5:1:3 as so...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3283825

Name: Retardation factor of the compound using n-BuOH-HOAc-EtOAc-H2O at ratio of 1:1:1:1 as...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3283828

Name: Retardation factor of the compound using EtOH-H2O at ratio of 7:3 as solvent system b...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3283827

Name: Retardation factor of the compound using n-PrOH-1N HOAc at ratio of 2:1 as solvent sy...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3283829

Name: Decrease in systemic arterial blood pressure in dog at 10 ng/kg, iv measured for 2 to...
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL3283831

Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100

Name: Decrease in systemic arterial blood pressure in dog at >5 ng/kg, iv measured for 2 to...
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL3283812

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[Tyr8 ]-substance P

substance PTyr8

L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Tyr-Gly-L-Leu-L-Met-NH2

RPKPQQFYGLM-NH2

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(Tyr8)-Substance P

Use of (Tyr8)-Substance P

Names

(Tyr8)-Substance P Biological Activity

Chemical & Physical Properties

(Tyr8)-Substance PBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.