Cyclo(Pro-Val)

Modify Date: 2025-08-25 16:57:14

Cyclo(Pro-Val) Structure
Cyclo(Pro-Val) structure
Common Name Cyclo(Pro-Val)
CAS Number 5654-87-5 Molecular Weight 196.25
Density 1.17g/cm3 Boiling Point 420.7ºC at 760 mmHg
Molecular Formula C10H16N2O2 Melting Point N/A
MSDS N/A Flash Point 208.2ºC

 Use of Cyclo(Pro-Val)


Cyclo(Pro-Val) can be isolated from Pseudomonas fluorescens GcM5-1A and has cytotoxicity[1].

 Names

Name 3-propan-2-yl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Synonym More Synonyms

 Cyclo(Pro-Val) Biological Activity

Description Cyclo(Pro-Val) can be isolated from Pseudomonas fluorescens GcM5-1A and has cytotoxicity[1].
Related Catalog
References

[1]. Guo Q, et al. Two Cyclic Dipeptides from Pseudomonas fluorescens GcM5-1A Carried by the Pine Wood Nematode and Their Toxicities to Japanese Black Pine Suspension Cells and Seedlings in vitro. J Nematol. 2007 Sep;39(3):243-7.  

 Chemical & Physical Properties

Density 1.17g/cm3
Boiling Point 420.7ºC at 760 mmHg
Molecular Formula C10H16N2O2
Molecular Weight 196.25
Flash Point 208.2ºC
Exact Mass 196.12100
PSA 49.41000
LogP 0.39850
Index of Refraction 1.535
InChIKey XLUAWXQORJEMBD-UHFFFAOYSA-N
SMILES CC(C)C1NC(=O)C2CCCN2C1=O

 Safety Information

HS Code 2933990090

 Synthetic Route

~%

Cyclo(Pro-Val) Structure

Cyclo(Pro-Val)

CAS#:5654-87-5

Literature: Lopez-Cobenas, Alberto; Cledera, Pilar; Sanchez, J. Domingo; Lopez-Alvarado, Pilar; Ramos, M. Teresa; Avendano, Carmen; Menendez, J. Carlos Synthesis, 2005 , # 19 art. no. C06905SS, p. 3412 - 3422

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Cyclo(Pro-Val)Bioassay

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Name: Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ...
Source: NCGC
External Id: s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1
Name: Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) naive MV4-11 ce...
Source: NCGC
External Id: s-sky_synergy-MV-411_N-CTG72-MIPE_NPC_NPACT_Kinase-p1
Name: Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
Source: NCGC
External Id: APP-Toga-CHIKV-nsp2-p
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1
2

 Synonyms

Cyclo-Val-Pro-diketopiperazine
cyclo-Pro-Val
Val-Pro-diketopiperazine
1,4-Dioxo-3-isopropyl-octahydropyrrolo<1,2-a>pyrazin
Diketopiperazin-Pro-Val
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