Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-10-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR)

Modify Date: 2026-08-06 07:39:01

Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-10-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR) structure	Common Name	Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-10-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR)
	CAS Number	568-53-6	Molecular Weight	400.38
	Density	1.336g/cm3	Boiling Point	625.4ºC at 760mmHg
	Molecular Formula	C₂₁H₂₀O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	221.2ºC

Use of Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-10-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR)

α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization [1].

Name	α-peltatin
Synonym	More Synonyms

Description	α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization [1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Avula B, et al. Rapid analysis of lignans from leaves of Podophyllum peltatum L. samples using UPLC-UV-MS. Biomed Chromatogr. 2011 Nov;25(11):1230-6.

Density	1.336g/cm3
Boiling Point	625.4ºC at 760mmHg
Molecular Formula	C₂₁H₂₀O₈
Molecular Weight	400.38
Flash Point	221.2ºC
Exact Mass	400.11600
PSA	103.68000
LogP	2.32090
Index of Refraction	1.573
InChIKey	JGGWNGRBXJWAOC-HKJPBSJPSA-N
SMILES	COc1cc(C2c3cc4c(c(O)c3CC3COC(=O)C32)OCO4)cc(OC)c1O

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LV2476800

CAS REGISTRY NUMBER :: 568-53-6

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C21-H18-O8

MOLECULAR WEIGHT :: 398.39

WISWESSER LINE NOTATION :: T E5 C665 FVO NO PO OHTT&&J DR DQ CO1 EO1& LQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Human HeLa cell

DOSE/DURATION :: 10 umol/L

REFERENCE :: BICHAW Biochemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1962- Volume(issue)/page/year: 15,5443,1976

Precursor 0
DownStream 1
CAS#:6270-40-2 10-ethoxy-5-(4-...

Name: Compound was tested for in vitro cytotoxicity in KB cells after 3 days of incubation
Source: ChEMBL
Target: N/A
External Id: CHEMBL885237

Name: Compound was tested for percentage inhibition against DNA topoisomerase II
Source: ChEMBL
Target: DNA topoisomerase 2-beta
External Id: CHEMBL669736

Name: Cytotoxicity against human primary amnion cells assessed as morphological changes by ...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL999159

Name: Antiviral activity against HSV1 infected in african green monkey Vero cells assessed ...
Source: ChEMBL
Target: Human alphaherpesvirus 1
External Id: CHEMBL1031698

Name: Antiviral activity against measles virus infected in african green monkey Vero cells ...
Source: ChEMBL
Target: Measles morbillivirus
External Id: CHEMBL1031696

Name: Antiviral activity against HSV1 infected in human primary amnion cells assessed as in...
Source: ChEMBL
Target: Human alphaherpesvirus 1
External Id: CHEMBL999158

Name: Antiviral activity against measles virus infected in african green monkey Vero cells ...
Source: ChEMBL
Target: Measles morbillivirus
External Id: CHEMBL1031697

Name: Inhibitory activity against strand transfer by HIV-1 Integrase at 100 uM
Source: ChEMBL
Target: Integrase
External Id: CHEMBL700694

Name: HIV Enzyme Data
Source: NIAID
Target: N/A
External Id: HIV Enzyme Data

Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data

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(5aR,8aR,9R)-4-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one

PELTATIN A

alpha-peltatin

NCI 1074

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Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-10-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR)

Use of Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-10-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR)

Names

Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Precursor & DownStream

Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.