8-methyladenosine

Modify Date: 2025-08-31 14:52:01

8-methyladenosine Structure
8-methyladenosine structure
Common Name 8-methyladenosine
CAS Number 56973-12-7 Molecular Weight 281.27
Density N/A Boiling Point N/A
Molecular Formula C11H15N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 8-methyladenosine


8-Methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name (2R,3R,4S,5R)-2-(6-amino-8-methylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Synonym More Synonyms

 8-methyladenosine Biological Activity

Description 8-Methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C11H15N5O4
Molecular Weight 281.27
Exact Mass 281.11200
PSA 139.54000
InChIKey RTGYRFMTJZYXPD-IOSLPCCCSA-N
SMILES Cc1nc2c(N)ncnc2n1C1OC(CO)C(O)C1O

 Synonyms

8-Methyl Ado
Adenosine,8-methyl
8-Methyladenosine
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