Nifenalol

Modify Date: 2024-01-11 12:26:42

Nifenalol Structure
Nifenalol structure
Common Name Nifenalol
CAS Number 5704-60-9 Molecular Weight 260.72
Density N/A Boiling Point N/A
Molecular Formula C11H17ClN2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nifenalol


Nifenalol hydrochloride is a β-adrenergic receptor antagonist. Nifenalol hydrochloride induces the Early Afterdepolarization (EAD) effect. EAD is a phenomenon in cardiac electrophysiology that usually occurs during an action potential in ventricular muscle cells and can lead to arrhythmia. The EAD effect of Nifenalol hydrochloride can be blocked by Tetrodotoxin. Nifenalol hydrochloride is used in the study of conditions such as irregular heartbeat or high blood pressure[1].

 Names

Name Nifenalol hydrochloride
Synonym More Synonyms

 Nifenalol Biological Activity

Description Nifenalol hydrochloride is a β-adrenergic receptor antagonist. Nifenalol hydrochloride induces the Early Afterdepolarization (EAD) effect. EAD is a phenomenon in cardiac electrophysiology that usually occurs during an action potential in ventricular muscle cells and can lead to arrhythmia. The EAD effect of Nifenalol hydrochloride can be blocked by Tetrodotoxin. Nifenalol hydrochloride is used in the study of conditions such as irregular heartbeat or high blood pressure[1].
Related Catalog
Target

β-adrenoceptor

References

[1]. Lemmens-Gruber R, et al. Arrhythmogenic effect of beta-adrenoceptor-blocking drugs in Purkinje fibres of guinea-pig hearts. Arch Int Pharmacodyn Ther. 1996 Jan-Feb;331(1):46-58.  

 Chemical & Physical Properties

Molecular Formula C11H17ClN2O3
Molecular Weight 260.72
Exact Mass 260.09300
PSA 78.08000
LogP 3.34230

 Safety Information

HS Code 2922199090

 Precursor & DownStream

Precursor  0

DownStream  1

 Customs

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

INPEA hydrochloride
N-isopropyl-p-nitrophenylethanolamine hydrochloride
Nifenalol
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