H-Gly-Sar-Sar-OH
Modify Date: 2024-01-16 19:29:45
H-Gly-Sar-Sar-OH structure
|
Common Name | H-Gly-Sar-Sar-OH | ||
|---|---|---|---|---|
| CAS Number | 57836-11-0 | Molecular Weight | 217.22200 | |
| Density | 1.28g/cm3 | Boiling Point | 406.5ºC at 760 mmHg | |
| Molecular Formula | C8H15N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 199.6ºC | |
Use of H-Gly-Sar-Sar-OHH-Gly-Sar-Sar-OH is an orally active tripeptide. H-Gly-Sar-Sar-OH is transported through PepT1 within Caco-2 cells. H-Gly Sar Sar OH has potential applications in material transportation[1][2][3]. |
| Name | h-gly-sar-sar-oh |
|---|
| Description | H-Gly-Sar-Sar-OH is an orally active tripeptide. H-Gly-Sar-Sar-OH is transported through PepT1 within Caco-2 cells. H-Gly Sar Sar OH has potential applications in material transportation[1][2][3]. |
|---|---|
| Related Catalog | |
| In Vivo | H-Gly-Sar-Sar-OH (0.1 mM；灌注；单剂量) 在 Sprague-Dawley 大鼠肾脏中未显著被水解 (给药 60 min) 或清除[2]。 H-Gly-Sar-Sar-OH (10 mg/kg；口服；单剂量) 在自发性高血压大鼠 (SHRs) 中显示出稳定性[3]。 H-Gly-Sar-Sar-OH 在自发性高血压大鼠中的药代动力学 (PK) 参数[3] Week old Cmax (nmol/mL, plasma) Tmax (min) AUC0-90 min (nmol•min/mL, plasma) T1/2 (min) 8 4.6±0.6 30 258.0±32.1 75 40 10.7±1.5 30 621.0±86.3 83 Animal Model: Male Sprague-Dawley rats (350 g)[2]. Dosage: 0.1 mM. Administration: Perfusion (kidney); single dose. Result: Showed stability. Animal Model: Male SHRs (8 and 40 week-old)[3]. Dosage: 10 mg/kg. Administration: Oral gavage; single dose. Result: Detected in full form. |
| References |
| Density | 1.28g/cm3 |
|---|---|
| Boiling Point | 406.5ºC at 760 mmHg |
| Molecular Formula | C8H15N3O4 |
| Molecular Weight | 217.22200 |
| Flash Point | 199.6ºC |
| Exact Mass | 217.10600 |
| PSA | 103.94000 |
| Index of Refraction | 1.519 |