2,2-Dimethyl-3-phenyl-4-(p-(beta-pyrrolidinoethoxy)phenyl)-7-methoxychromene hydrochloride

Modify Date: 2024-01-27 18:08:34

2,2-Dimethyl-3-phenyl-4-(p-(beta-pyrrolidinoethoxy)phenyl)-7-methoxychromene hydrochloride Structure
2,2-Dimethyl-3-phenyl-4-(p-(beta-pyrrolidinoethoxy)phenyl)-7-methoxychromene hydrochloride structure
Common Name 2,2-Dimethyl-3-phenyl-4-(p-(beta-pyrrolidinoethoxy)phenyl)-7-methoxychromene hydrochloride
CAS Number 57897-49-1 Molecular Weight 492.04900
Density 1.128g/cm3 Boiling Point 584ºC at 760 mmHg
Molecular Formula C30H34ClNO3 Melting Point N/A
MSDS N/A Flash Point 155.9ºC

 Names

Name 1-[2-[4-(7-methoxy-2,2-dimethyl-3-phenylchromen-4-yl)phenoxy]ethyl]pyrrolidine,hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.128g/cm3
Boiling Point 584ºC at 760 mmHg
Molecular Formula C30H34ClNO3
Molecular Weight 492.04900
Flash Point 155.9ºC
Exact Mass 491.22300
PSA 30.93000
LogP 7.03980

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY0916000
CHEMICAL NAME :
Pyrrolidine, 1-(2-(4-(2,2-dimethyl-7-methoxy-3-phenyl-2H-1-benzopy ran-4-yl)phenoxy)ethy l)-, hydrochloride
CAS REGISTRY NUMBER :
57897-49-1
LAST UPDATED :
198910
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C30-H33-N-O3.Cl-H
MOLECULAR WEIGHT :
492.10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJSIDW Indian Journal of Pharmaceutical Sciences. (Kalina, Santa Cruz (East), Bombay 400 029, India) V.40(2)- 1978- Volume(issue)/page/year: 49,43,1987 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
25 mg/kg
SEX/DURATION :
female 1-5 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 19,276,1976

 Synonyms

1-(2-(4-(2,2-Dimethyl-7-methoxy-3-phenyl-2H-1-benzopyran-4-yl)phenoxy)ethyl)pyrrolidine HCl
Pyrrolidine,1-(2-(4-(2,2-dimethyl-7-methoxy-3-phenyl-2H-1-benzopyran-4-yl)phenoxy)ethyl)-,hydrochloride
1-[2-[4-(7-methoxy-2,2-dimethyl-3-phenylchromen-4-yl)phenoxy]ethyl]pyrrolidine hydrochloride