5-Carboxymethyl-2-thiouridine

Modify Date: 2024-01-15 07:08:48

5-Carboxymethyl-2-thiouridine Structure
5-Carboxymethyl-2-thiouridine structure
Common Name 5-Carboxymethyl-2-thiouridine
CAS Number 58479-77-9 Molecular Weight 318.30
Density N/A Boiling Point N/A
Molecular Formula C11H14N2O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Carboxymethyl-2-thiouridine


5-Carboxymethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-2-sulfanylidenepyrimidin-5-yl]acetic acid
Synonym More Synonyms

 5-Carboxymethyl-2-thiouridine Biological Activity

Description 5-Carboxymethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C11H14N2O7S
Molecular Weight 318.30
Exact Mass 318.05200
PSA 177.36000

 Synonyms

2-Thio-5-carboxymethyluridine