5-phenyl-1,3,4-oxathiazol-2-one

Modify Date: 2025-08-27 18:19:38

5-phenyl-1,3,4-oxathiazol-2-one Structure
5-phenyl-1,3,4-oxathiazol-2-one structure
Common Name 5-phenyl-1,3,4-oxathiazol-2-one
CAS Number 5852-49-3 Molecular Weight 179.19600
Density N/A Boiling Point N/A
Molecular Formula C8H5NO2S Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 5-phenyl-1,3,4-oxathiazol-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C8H5NO2S
Molecular Weight 179.19600
Exact Mass 179.00400
PSA 71.34000
LogP 1.76330
InChIKey NDAURKDIFHXVHE-UHFFFAOYSA-N
SMILES O=c1oc(-c2ccccc2)ns1

 Synthetic Route

~73%

5-phenyl-1,3,4-oxathiazol-2-one Structure

5-phenyl-1,3,4-...

CAS#:5852-49-3

Literature: Wai, Kwok-Fai; Sammes, Michael P. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 1 p. 183 - 187

~%

Detail
Literature: Monsanto Company Patent: US4144047 A1, 1979 ;

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5-phenyl-1,3,4-oxathiazol-2-one Structure

5-phenyl-1,3,4-...

CAS#:5852-49-3

Literature: Koval', I. V.; Oleinik, T. G.; Tarasenko, A. I.; Kremlev, M. M. Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 12 p. 2358 - 2365 Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 12 p. 2578 - 2587

~47%

5-phenyl-1,3,4-oxathiazol-2-one Structure

5-phenyl-1,3,4-...

CAS#:5852-49-3

Literature: Koval', I. V.; Tarasenko, A. I.; Panchenko, I. S.; Molchanova, N. R. Journal of Organic Chemistry USSR (English Translation), 1986 , p. 1538 - 1541 Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 8 p. 1712 - 1715

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5-phenyl-1,3,4-oxathiazol-2-one Structure

5-phenyl-1,3,4-...

CAS#:5852-49-3

Literature: Senning,A.; Kelly,P. Acta Chemica Scandinavica (1947-1973), 1967 , vol. 21, p. 1871 - 1878

 5-phenyl-1,3,4-oxathiazol-2-oneBioassay

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Name: Ratio of Kinact/Ki for immunoproteasome-20S subunit beta5i in human PBMC to Kinact/Ki...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3266566
Name: Selectivity for Trypanosoma cruzi triosephosphate isomerase over human triosephosphat...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1641185
Name: Antiparasitic activity against Trypanosoma cruzi T2 epimastigotes assessed as growth ...
Source: ChEMBL
Target: Trypanosoma cruzi
External Id: CHEMBL1641186
Name: Antiparasitic activity against Trypanosoma cruzi T2 epimastigotes assessed as growth ...
Source: ChEMBL
Target: Trypanosoma cruzi
External Id: CHEMBL1641187
Name: Ratio of Kinact to Ki for immunoproteasome-20S subunit beta5i in human PBMC using suc...
Source: ChEMBL
Target: Proteasome subunit beta type-8
External Id: CHEMBL3266555
Name: Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate...
Source: ChEMBL
Target: Proteasome subunit beta type-8
External Id: CHEMBL3266190
Name: Inhibition of Trypanosoma cruzi triosephosphate isomerase at 100 uM after 2 hrs
Source: ChEMBL
Target: Triosephosphate isomerase, glycosomal
External Id: CHEMBL1641189
Name: Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate...
Source: ChEMBL
Target: Proteasome subunit beta type-8
External Id: CHEMBL3266557
Name: Inhibition of Trypanosoma cruzi triosephosphate isomerase at 400 uM after 2 hrs
Source: ChEMBL
Target: Triosephosphate isomerase, glycosomal
External Id: CHEMBL1641190
Name: Inhibition of constitutive proteasome 20S subunit beta5c in human RBC assessed as sub...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3266556
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 Synonyms

5-phenyl-[1,3,4]oxathiazol-2-one
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