(Z)-3-(9-octadecenyloxy)propane-1,2-diol

Modify Date: 2024-01-05 22:30:18

(Z)-3-(9-octadecenyloxy)propane-1,2-diol Structure
(Z)-3-(9-octadecenyloxy)propane-1,2-diol structure
Common Name (Z)-3-(9-octadecenyloxy)propane-1,2-diol
CAS Number 593-31-7 Molecular Weight 342.55600
Density 0.924g/cm3 Boiling Point 470.6ºC at 760mmHg
Molecular Formula C21H42O3 Melting Point N/A
MSDS N/A Flash Point 238.4ºC

 Use of (Z)-3-(9-octadecenyloxy)propane-1,2-diol


Selachyl alcohol is an orally active antihypertensive agent. Selachyl alcohol has similar activities with antihypertensive neutral renomedullary lipid (ANRL). Selachyl alcohol is an alkylglycerol compound in shark liver oil mixture with properties that reduce lung metastasis. Selachyl alcohol can be used for cardiovascular disease research[1][2].

 Names

Name 3-[(E)-octadec-9-enoxy]propane-1,2-diol
Synonym More Synonyms

 (Z)-3-(9-octadecenyloxy)propane-1,2-diol Biological Activity

Description Selachyl alcohol is an orally active antihypertensive agent. Selachyl alcohol has similar activities with antihypertensive neutral renomedullary lipid (ANRL). Selachyl alcohol is an alkylglycerol compound in shark liver oil mixture with properties that reduce lung metastasis. Selachyl alcohol can be used for cardiovascular disease research[1][2].
Related Catalog
In Vivo Selachyl alcohol (5 和 10 mg,灌胃,5 次;1 mg,静脉注射,1 次) 降低高血压小鼠的血压[1]。 Animal Model: Male Sprague-Dawley rats with hypertension[1] Dosage: 5 and 10 mg (oral gavage); 1 mg (i.v.) Administration: Oral gavage, 5 and 10 mg, 10 occasions; intravenous injection, 1 mg, once Result: Induced blood pressure drops slowly about 60 mm Hg and remains for 20 minutes. Effectively reduced blood pressure by gastrointestinal tract.
References

[1]. Muirhead EE, et al. Selachyl alcohol as an oral antihypertensive agent: a preliminary note. Am J Med Sci. 1987 Nov;294(5):384-7.  

[2]. Momha R, et al. Anti-Angiogenic and Cytotoxicity Effects of Selachyl Alcohol Analogues. Anticancer Agents Med Chem. 2022;22(10):1913-1920.  

 Chemical & Physical Properties

Density 0.924g/cm3
Boiling Point 470.6ºC at 760mmHg
Molecular Formula C21H42O3
Molecular Weight 342.55600
Flash Point 238.4ºC
Exact Mass 342.31300
PSA 49.69000
LogP 5.39370
Index of Refraction 1.474

 Synonyms

Glyceryl monooleyl ether
1-oleylglycerol
3-octadec-9c-enyloxy-propane-1,2-diol
1-glyceryl monoleyl ether
EINECS 209-787-7
selachyl alcohol
1-O-cis-9-octadecenylglycerol
Octadec-9-enylglycerol
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