3-(4-methoxyphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione

Modify Date: 2025-08-29 23:20:52

3-(4-methoxyphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione Structure
3-(4-methoxyphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione structure
Common Name 3-(4-methoxyphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione
CAS Number 59618-77-8 Molecular Weight 326.37000
Density N/A Boiling Point N/A
Molecular Formula C17H14N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 3-(4-methoxyphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C17H14N2O3S
Molecular Weight 326.37000
Exact Mass 326.07300
PSA 87.43000
LogP 2.73020
InChIKey RLJZCFZGIVVNEA-UHFFFAOYSA-N
SMILES COc1ccc(N2C(=O)CSC23C(=O)Nc2ccccc23)cc1

 Synthetic Route

~90%

3-(4-methoxyphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione Structure

3-(4-methoxyphe...

CAS#:59618-77-8

Literature: Azizian, Javad; Morady, Ali Varasteh; Jadidi, Khosrow; Mehrdad, Morteza; Sarrafi, Yaghob Synthetic Communications, 2000 , vol. 30, # 3 p. 537 - 542

~%

3-(4-methoxyphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione Structure

3-(4-methoxyphe...

CAS#:59618-77-8

Literature: Joshi, Krishna C.; Patni, R.; Chand, Pooran Heterocycles, 1981 , vol. 16, # 9 p. 1555 - 1559

~%

3-(4-methoxyphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione Structure

3-(4-methoxyphe...

CAS#:59618-77-8

Literature: Joshi, Krishna C.; Patni, R.; Chand, Pooran Heterocycles, 1981 , vol. 16, # 9 p. 1555 - 1559

~%

3-(4-methoxyphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione Structure

3-(4-methoxyphe...

CAS#:59618-77-8

Literature: Panda, Siva S.; Jain, Subhash C. Monatshefte fur Chemie, 2012 , vol. 143, # 8 p. 1187 - 1194

 Bioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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 Synonyms

HMS623P03
HMS2327L15
3'-(4-methoxyphenyl)-spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione
3'-(p-anisoyl)-spiro[3H-indole-3,2'-thiazolidine]-2,4'(1H)-dione
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