N-pyridin-4-ylbenzene-1,4-diamine

Modify Date: 2025-09-12 17:26:45

N-pyridin-4-ylbenzene-1,4-diamine Structure
N-pyridin-4-ylbenzene-1,4-diamine structure
Common Name N-pyridin-4-ylbenzene-1,4-diamine
CAS Number 60172-08-9 Molecular Weight 185.22500
Density 1.226g/cm3 Boiling Point 382.9ºC at 760 mmHg
Molecular Formula C11H11N3 Melting Point N/A
MSDS N/A Flash Point 185.4ºC

 Names

Name 4-N-pyridin-4-ylbenzene-1,4-diamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.226g/cm3
Boiling Point 382.9ºC at 760 mmHg
Molecular Formula C11H11N3
Molecular Weight 185.22500
Flash Point 185.4ºC
Exact Mass 185.09500
PSA 50.94000
LogP 3.06160
Index of Refraction 1.693
InChIKey BGFGRYYEROKAHI-UHFFFAOYSA-N
SMILES Nc1ccc(Nc2ccncc2)cc1

 Synthetic Route

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N-pyridin-4-ylbenzene-1,4-diamine Structure

N-pyridin-4-ylb...

CAS#:60172-08-9

Literature: SUPERGEN, INC. Patent: WO2008/46085 A2, 2008 ; Location in patent: Page/Page column 56 ; WO 2008/046085 A2

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N-pyridin-4-ylbenzene-1,4-diamine Structure

N-pyridin-4-ylb...

CAS#:60172-08-9

Literature: Burgeson, James R.; Moore, Amy L.; Boutilier, Jordan K.; Cerruti, Natasha R.; Gharaibeh, Dima N.; Lovejoy, Candace E.; Amberg, Sean M.; Hruby, Dennis E.; Tyavanagimatt, Shanthakumar R.; Allen III, Robert D.; Dai, Dongcheng Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4263 - 4272

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N-pyridin-4-ylbenzene-1,4-diamine Structure

N-pyridin-4-ylb...

CAS#:60172-08-9

Literature: Burgeson, James R.; Moore, Amy L.; Boutilier, Jordan K.; Cerruti, Natasha R.; Gharaibeh, Dima N.; Lovejoy, Candace E.; Amberg, Sean M.; Hruby, Dennis E.; Tyavanagimatt, Shanthakumar R.; Allen III, Robert D.; Dai, Dongcheng Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4263 - 4272

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N-pyridin-4-ylbenzene-1,4-diamine Structure

N-pyridin-4-ylb...

CAS#:60172-08-9

Literature: Gamage, Swarna A.; Brooke, Darby G.; Redkar, Sanjeev; Datta, Jharna; Jacob, Samson T.; Denny, William A. Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 11 p. 3147 - 3153

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N-pyridin-4-ylbenzene-1,4-diamine Structure

N-pyridin-4-ylb...

CAS#:60172-08-9

Literature: Gamage, Swarna A.; Brooke, Darby G.; Redkar, Sanjeev; Datta, Jharna; Jacob, Samson T.; Denny, William A. Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 11 p. 3147 - 3153

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N-pyridin-4-ylbenzene-1,4-diamine Structure

N-pyridin-4-ylb...

CAS#:60172-08-9

Detail
Literature: Buncel, Erwin; Cheon, Kap-Soo Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 5 p. 1241 - 1247

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N-pyridin-4-ylbenzene-1,4-diamine Structure

N-pyridin-4-ylb...

CAS#:60172-08-9

Detail
Literature: Buncel, Erwin; Cheon, Kap-Soo Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 5 p. 1241 - 1247

 N-pyridin-4-ylbenzene-1,4-diamineBioassay

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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
Name: Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Bas...
Source: Broad Institute
Target: N/A
External Id: 2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Prima...
Source: NCGC
Target: apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7]
External Id: AMA1100
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: abhydrolase domain-containing protein 4 isoform 1 [Mus musculus]
External Id: ABHD4_INH_FP_1536_1X%INH PRUN
Name: High Throughput Screen to Identify Inhibitors Targeting HIV-1 Vif-dependent Degradati...
Source: Southern Research Institute
Target: HIV-1 Vif
External Id: HIV1-VIF_MS
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 Synonyms

N-4-pyridinyl-1,4-benzenediamine
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