3-hydroxyoxindole

Modify Date: 2025-08-26 00:02:33

3-hydroxyoxindole Structure
3-hydroxyoxindole structure
Common Name 3-hydroxyoxindole
CAS Number 61-71-2 Molecular Weight 149.14700
Density 1.38g/cm3 Boiling Point 368.2ºC at 760 mmHg
Molecular Formula C8H7NO2 Melting Point N/A
MSDS N/A Flash Point 176.5ºC

 Names

Name 3-hydroxyindolin-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.38g/cm3
Boiling Point 368.2ºC at 760 mmHg
Molecular Formula C8H7NO2
Molecular Weight 149.14700
Flash Point 176.5ºC
Exact Mass 149.04800
PSA 49.33000
LogP 0.81010
Index of Refraction 1.639
InChIKey SGZFJWQQBHYNNF-UHFFFAOYSA-N
SMILES O=C1Nc2ccccc2C1O

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NM3289460
CHEMICAL NAME :
2H-Indol-2-one, 1,3-dihydro-3-hydroxy-
CAS REGISTRY NUMBER :
61-71-2
BEILSTEIN REFERENCE NO. :
0082628
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H7-N-O2
MOLECULAR WEIGHT :
149.16
WISWESSER LINE NOTATION :
T56 BMV DHJ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 19,562,1985

 Safety Information

HS Code 2933790090

 Synthetic Route

 Customs

HS Code 2933790090
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

 3-hydroxyoxindoleBioassay

View more

Name: Phenotypic growth assay for Mycobacterium tuberculosis grown for 4 days on DPPC, chol...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4649948
Name: Phenotypic growth assay for Mycobacterium tuberculosis grown for 3 days on 7H9, gluco...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4649949
Name: Antibacterial activity against Acinetobacter baumannii ATCC 19606 (CO-ADD:GN_034); MI...
Source: ChEMBL
Target: Acinetobacter baumannii
External Id: CHEMBL4296188
Name: Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 (CO-ADD:GN_042); MIC...
Source: ChEMBL
Target: Pseudomonas aeruginosa
External Id: CHEMBL4296187
Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
Name: Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as subs...
Source: ChEMBL
Target: D-amino-acid oxidase
External Id: CHEMBL2154050
Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
Name: Antibacterial activity against Pseudomonas aeruginosa PAO397 [PAO1 d(mexAB-oprM) d(me...
Source: ChEMBL
Target: Pseudomonas aeruginosa
External Id: CHEMBL4296802
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 Synonyms

2,3-dihydro-3-hydroxy-2-oxo-1H-indole
Dioxindole
3-hydroxyoxindole
3-Hydroxy-2-oxoindole
3-hydroxy-1,3-dihydroindol-2-one
3-hydroxy-2-oxindole
1,3-Dihydro-3-hydroxy-2H-indol-2-one
2-Indolinone,3-hydroxy
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