β-Amino Acid Imagabalin Hydrochloride

Modify Date: 2024-01-09 19:16:32

β-Amino Acid Imagabalin Hydrochloride Structure
β-Amino Acid Imagabalin Hydrochloride structure
Common Name β-Amino Acid Imagabalin Hydrochloride
CAS Number 610300-00-0 Molecular Weight 209.71400
Density N/A Boiling Point N/A
Molecular Formula C9H20ClNO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of β-Amino Acid Imagabalin Hydrochloride


β-Amino Acid Imagabalin Hydrochloride (PD-0332334) is a ligand for the α2δ subunit of the voltage-dependent calcium channel.

 Names

Name (3S,5R)-3-amino-5-methyloctanoic acid,hydrochloride
Synonym More Synonyms

 β-Amino Acid Imagabalin Hydrochloride Biological Activity

Description β-Amino Acid Imagabalin Hydrochloride (PD-0332334) is a ligand for the α2δ subunit of the voltage-dependent calcium channel.
Related Catalog
Target

Calcium channel[1]

In Vivo β-Amino Acid Imagabalin Hydrochloride had been in phase III clinical trials for the treatment of generalised anxiety disorders. However, this research has been discontinued[2]. β-Amino Acid Imagabalin Hydrochloride had been also in phase I clinical trials for the treatment of chronic kidney disease[3].
References

[1]. Birch M, et al. A Simplified Process for the Manufacture of Imagabalin Hydrochloride (PD-0332334), an α2δ-Ligand for the Treatment of Generalised Anxiety Disorder. Org. Process Res. Dev., 2011, 15 (6), pp 1358–1364

 Chemical & Physical Properties

Molecular Formula C9H20ClNO2
Molecular Weight 209.71400
Exact Mass 209.11800
PSA 63.32000
LogP 3.11700

 Synonyms

Imagabalin HCl
UNII-MJ3F8ZA7Q1
β-Amino Acid Imagabalin Hydrochloride
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