(S,E)-Ethyl 2,5-Dimethyl-4-(Methylamino)Hex-2-Enoate Hydrochloride

Modify Date: 2024-06-26 18:28:06

(S,E)-Ethyl 2,5-Dimethyl-4-(Methylamino)Hex-2-Enoate Hydrochloride Structure
(S,E)-Ethyl 2,5-Dimethyl-4-(Methylamino)Hex-2-Enoate Hydrochloride structure
Common Name (S,E)-Ethyl 2,5-Dimethyl-4-(Methylamino)Hex-2-Enoate Hydrochloride
CAS Number 610786-69-1 Molecular Weight 235.75
Density N/A Boiling Point N/A
Molecular Formula C11H22ClNO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S,E)-Ethyl 2,5-Dimethyl-4-(Methylamino)Hex-2-Enoate Hydrochloride


Taltobulin intermediate-3 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].

 Names

Name 2-Hexenoic acid, 2,5-dimethyl-4-(methylamino)-, ethyl ester, hydrochloride, (2E,4S)-
Synonym More Synonyms

  Biological Activity

Description Taltobulin intermediate-3 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].
Related Catalog
References

[1]. Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45.  

 Chemical & Physical Properties

Molecular Formula C11H22ClNO2
Molecular Weight 235.75
Exact Mass 235.133911

 Synonyms

Ethyl (2E,4S)-2,5-dimethyl-4-(methylamino)-2-hexenoate hydrochloride (1:1)
MFCD29472351
2-Hexenoic acid, 2,5-dimethyl-4-(methylamino)-, ethyl ester, (2E,4S)-, hydrochloride (1:1)
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