(Z)-α-Cyanostilbene

Modify Date: 2025-12-04 11:44:40

(Z)-α-Cyanostilbene Structure
(Z)-α-Cyanostilbene structure
Common Name (Z)-α-Cyanostilbene
CAS Number 6114-57-4 Molecular Weight 205.25
Density N/A Boiling Point N/A
Molecular Formula C15H11N Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (Z)-α-Cyanostilbene


(Z)-α-Cyanostilbene (compound 8), a dicyano substituted acrylonitrile, shows selective antiproliferative activity against HeLa and HepG2 cells, with IC50s of 0.33 and 0.52 μM, respectively[1].

 Names

Name (Z)-α-Cyanostilbene

 (Z)-α-Cyanostilbene Biological Activity

Description (Z)-α-Cyanostilbene (compound 8), a dicyano substituted acrylonitrile, shows selective antiproliferative activity against HeLa and HepG2 cells, with IC50s of 0.33 and 0.52 μM, respectively[1].
Related Catalog
References

[1]. Perin N, et, al. Antiproliferative activity and mode of action analysis of novel amino and amido substituted phenantrene and naphtho[2,1-b]thiophene derivatives. Eur J Med Chem. 2020 Jan 1;185:111833.

 Chemical & Physical Properties

Molecular Formula C15H11N
Molecular Weight 205.25

 (Z)-α-CyanostilbeneBioassay

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Name: Displacement of fluormone Pan-PPAR Green from mouse recombinant GST-tagged PPARbeta/d...
Source: ChEMBL
Target: Peroxisome proliferator-activated receptor delta
External Id: CHEMBL2033573
Name: Cytotoxicity against HFF cells assessed as reduction in cell viability incubated for ...
Source: ChEMBL
Target: HFF
External Id: CHEMBL4316451
Name: Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assa...
Source: ChEMBL
Target: SW-620
External Id: CHEMBL4316450
Name: Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assa...
Source: ChEMBL
Target: HepG2
External Id: CHEMBL4316449
Name: Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
Source: ChEMBL
Target: HeLa
External Id: CHEMBL4316448
Name: Antiproliferative activity against human CFPAC-1 cells incubated for 72 hrs by MTT as...
Source: ChEMBL
Target: CFPAC-1
External Id: CHEMBL4316447
Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data
Name: Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
Source: ChEMBL
Target: A549
External Id: CHEMBL4316446
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