(1S)-Calcitriol

Modify Date: 2024-01-11 16:09:38

(1S)-Calcitriol Structure
(1S)-Calcitriol structure
Common Name (1S)-Calcitriol
CAS Number 61476-45-7 Molecular Weight 416.64
Density N/A Boiling Point N/A
Molecular Formula C27H44O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (1S)-Calcitriol


(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1].

 Names

Name (1S)-Calcitriol

 (1S)-Calcitriol Biological Activity

Description (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1].
Related Catalog
In Vitro 3‐epi‐Calcitroic acid is an end product of (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3; 3‐epi‐1a,25(OH)2D3) metabolism by rat CYP24A1[1].
References

[1]. Steve Y Rhieu, et al. Metabolic stability of 3-epi-1α,25-dihydroxyvitamin D3 over 1 α 25-dihydroxyvitamin D3: metabolism and molecular docking studies using rat CYP24A1. J Cell Biochem. 2013 Oct;114(10):2293-305.

 Chemical & Physical Properties

Molecular Formula C27H44O3
Molecular Weight 416.64
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