tert-butyl 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate

Modify Date: 2025-09-12 07:38:32

tert-butyl 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate Structure
tert-butyl 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate structure
Common Name tert-butyl 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate
CAS Number 624734-26-5 Molecular Weight 302.29200
Density N/A Boiling Point N/A
Molecular Formula C14H17F3N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name tert-butyl 3-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridine-6-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C14H17F3N2O2
Molecular Weight 302.29200
Exact Mass 302.12400
PSA 42.43000
LogP 3.33150

 Synthetic Route

~46%

tert-butyl 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate Structure

tert-butyl 3-(t...

CAS#:624734-26-5

Literature: Goble, Stephen D.; Yang, Lihu; Zhou, Changyou; Kothandaraman, Shankaran; Guiadeen, Deodialsingh; Butora, Gabor; Pastemak, Alexander; Mills, Sander G. Patent: US2007/117797 A1, 2007 ; Location in patent: Page/Page column 24 ; US 20070117797 A1

~46%

tert-butyl 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate Structure

tert-butyl 3-(t...

CAS#:624734-26-5

Literature: MERCK and CO., INC. Patent: WO2005/105092 A2, 2005 ; Location in patent: Page/Page column 34 ; WO 2005/105092 A2

~%

tert-butyl 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate Structure

tert-butyl 3-(t...

CAS#:624734-26-5

Literature: JANSSEN PHARMACEUTICA NV; LANTER, James, C.; MARKOTAN, Thomas, P.; SUBASINGHE, Nalin; SUI, Zhihua Patent: WO2011/159854 A1, 2011 ; Location in patent: Page/Page column 197 ; WO 2011/159854 A1

 Synonyms

6-(tert-butoxycarbonyl)-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine
N-(tert-butoxycarbonyl)-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine
tert-Butyl 3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate
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