Dihydrolycorine

Modify Date: 2024-01-08 18:24:14

Dihydrolycorine structure	Common Name	Dihydrolycorine
	CAS Number	6271-21-2	Molecular Weight	289.326
	Density	1.5±0.1 g/cm3	Boiling Point	460.5±45.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₉NO₄	Melting Point	247℃
	MSDS	N/A	Flash Point	232.3±28.7 °C

Use of Dihydrolycorine

Dihydrolycorine is isolated from Lycoris radiate Herb with antihypertensive and neuroprotective activities[1]. Dihydrolycorine is an inhibitor of protein synthesis in eukarytic cells by inhibiting the peptide bone formation step[2].

Name	α-dihydrolycorine
Synonym	More Synonyms

Description	Dihydrolycorine is isolated from Lycoris radiate Herb with antihypertensive and neuroprotective activities[1]. Dihydrolycorine is an inhibitor of protein synthesis in eukarytic cells by inhibiting the peptide bone formation step[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	Protein synthesis[2]
In Vivo	Dihydrolycorine reduces infarct size, cerebral edema, and myeloperoxidase activity in a rat model of focal cerebral ischemia-reperfusion injury when administered following reperfusion[1]. Dihydrolycorine inhibits methoxamine-induced contraction of isolated rabbit aortic rings and rat anococcygeus muscle with pA2 values of 5.93 and 6.35, respectively[3].
References	[1]. JIANG Shi-qin, et al. Therapeutic Effects of Dihydrolycorine on Focal Cerebral Ischemia-reperfusion Injury in Rats. 《Journal of Yunyang Medical College》 2009-05 [2]. Jimenez A, et al. Inhibitors of protein synthesis in eukarytic cells. Comparative effects of some amaryllidaceae alkaloids. Biochim Biophys Acta. 1976 Mar 17;425(3):342-8. [3]. Chen BY, et al. [Hypotensive effect of dihydrolycorine]. Zhongguo Yao Li Xue Bao. 1993 Jan;14(1):45-9.

Density	1.5±0.1 g/cm3
Boiling Point	460.5±45.0 °C at 760 mmHg
Melting Point	247℃
Molecular Formula	C₁₆H₁₉NO₄
Molecular Weight	289.326
Flash Point	232.3±28.7 °C
Exact Mass	289.131409
PSA	62.16000
LogP	0.85
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.701

(1S,2S,3aR,12bS,12cR)-2,3,3a,4,5,7,12b,12c-Octahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol

Dihydrolycorine

1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,3,3a,4,5,7,12b,12c-octahydro-, (1S,2S,3aR,12bS,12cR)-

ihydrolycorine

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Dihydrolycorine
Price: ￥588.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Dihydrolycorine
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: dihydrolycorine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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