Tinazoline

Modify Date: 2024-07-19 08:32:11

Tinazoline Structure
Tinazoline structure
Common Name Tinazoline
CAS Number 62882-99-9 Molecular Weight 217.29000
Density 1.42g/cm3 Boiling Point 437.6ºC at 760 mmHg
Molecular Formula C11H11N3S Melting Point N/A
MSDS N/A Flash Point 218.4ºC

 Use of Tinazoline


Tinazoline, imidazole derivative, is a vasoconstrictor. Tinazoline can as nasal decongestant for the research of common cold[1].

 Names

Name 3-(4,5-Dihydro-1H-imidazol-2-ylsulfanyl)-1H-indole
Synonym More Synonyms

 Tinazoline Biological Activity

Description Tinazoline, imidazole derivative, is a vasoconstrictor. Tinazoline can as nasal decongestant for the research of common cold[1].
Related Catalog
References

[1]. Nagarajan K, et al. Structure activity relations among cyclic & acyclic S-(3-indolyl) isothioureas-development of a potent vasoconstrictor, tinazoline, 3-(2-imidazolin-2-yl-thio)indole. Indian J Exp Biol. 1981 Dec;19(12):1150-3.  

 Chemical & Physical Properties

Density 1.42g/cm3
Boiling Point 437.6ºC at 760 mmHg
Molecular Formula C11H11N3S
Molecular Weight 217.29000
Flash Point 218.4ºC
Exact Mass 217.06700
PSA 65.48000
LogP 1.98360
Index of Refraction 1.755

 Synthetic Route

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Tinazoline Structure

Tinazoline

CAS#:62882-99-9

Literature: Nagarajan, K.; Arya, V. P.; Parthasarathy, T. N.; Shenoy, S. J.; Shah, R. K.; Kulkarni, Y. S. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 8 p. 672 - 679

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Tinazoline Structure

Tinazoline

CAS#:62882-99-9

Literature: Nagarajan, K.; Arya, V. P.; Parthasarathy, T. N.; Shenoy, S. J.; Shah, R. K.; Kulkarni, Y. S. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 8 p. 672 - 679

 Synonyms

3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-benzo[d]isoxazole,monohydrochloride
3-(2-Imidazolin-2-yl)methyl-1,2-benzisoxazole hydrochloride
3-(2-imidazolin-2-ylthio)-indole
3-(2-Imidazolin-2-ylthio)-indol
3-(4,5-dihydro-1H-imidazol-2-ylsulfanyl)-indole