methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate

Modify Date: 2024-01-02 18:27:55

methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate Structure
methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate structure
Common Name methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate
CAS Number 62978-52-3 Molecular Weight 319.22700
Density 1.244g/cm3 Boiling Point 437.6ºC at 760 mmHg
Molecular Formula C14H20Cl2N2O2 Melting Point N/A
MSDS N/A Flash Point 218.5ºC

 Names

Name methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.244g/cm3
Boiling Point 437.6ºC at 760 mmHg
Molecular Formula C14H20Cl2N2O2
Molecular Weight 319.22700
Flash Point 218.5ºC
Exact Mass 318.09000
PSA 55.56000
LogP 2.71370
Index of Refraction 1.565

 Synthetic Route

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methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate Structure

methyl 2-amino-...

CAS#:62978-52-3

Literature: GURJAR, MUKUND KESHAV; Tripathy, Narendra Kumar; Kotharkar, Sandeep Anilrao; Patil, Pradip Nana; Mehta, Samit Satish Patent: US2012/116117 A1, 2012 ; Location in patent: Page/Page column 2 ;

~56%

methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate Structure

methyl 2-amino-...

CAS#:62978-52-3

Literature: Hsieh, Kun-hwa; Marshall, Garland R. Journal of Medicinal Chemistry, 1981 , vol. 24, # 11 p. 1304 - 1310

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methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate Structure

methyl 2-amino-...

CAS#:62978-52-3

Literature: Weerapreeyakul, Natthida; Visser, Petra; Brummelhuis, Mathijn; Gharat, Laxmikant; Chikhale, Prashant J. Medicinal Chemistry Research, 2000 , vol. 10, # 3 p. 148 - 163

 Synonyms

melphalan methyl ester hydrochloride salt
melphalan methylester hydrochloride