methyl 2-amino-5-bromo-3-nitrobenzoate

Modify Date: 2024-01-22 20:16:02

methyl 2-amino-5-bromo-3-nitrobenzoate Structure
methyl 2-amino-5-bromo-3-nitrobenzoate structure
Common Name methyl 2-amino-5-bromo-3-nitrobenzoate
CAS Number 636581-61-8 Molecular Weight 275.05600
Density 1.744g/cm3 Boiling Point 359.9ºC at 760 mmHg
Molecular Formula C8H7BrN2O4 Melting Point N/A
MSDS N/A Flash Point 171.5ºC

 Names

Name methyl 2-amino-5-bromo-3-nitrobenzoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.744g/cm3
Boiling Point 359.9ºC at 760 mmHg
Molecular Formula C8H7BrN2O4
Molecular Weight 275.05600
Flash Point 171.5ºC
Exact Mass 273.95900
PSA 98.14000
LogP 2.83050
Index of Refraction 1.635

 Safety Information

HS Code 2922499990

 Synthetic Route

~81%

methyl 2-amino-5-bromo-3-nitrobenzoate Structure

methyl 2-amino-...

CAS#:636581-61-8

Literature: VERTEX PHARMACEUTICALS INCORPORATED Patent: WO2003/105846 A1, 2003 ; Location in patent: Page 48 ; WO 03/105846 A1

~83%

methyl 2-amino-5-bromo-3-nitrobenzoate Structure

methyl 2-amino-...

CAS#:636581-61-8

Literature: PROLYSIS LTD. Patent: WO2007/148093 A1, 2007 ; Location in patent: Page/Page column 56-57 ; WO 2007/148093 A1

~93%

methyl 2-amino-5-bromo-3-nitrobenzoate Structure

methyl 2-amino-...

CAS#:636581-61-8

Literature: MERCK SERONO S.A.; THUNUGUNTLA, Siva Sanjeeva Rao; SUBRAMANYA, Hosahalli; KUNNAM, Satish Reddy; SANIVARU VIJAY, Sekhar Reddy; BINGI, Chakrapani; KUSANUR, Raviraj; SCHWARZ, Matthias; ARLT, Michael Patent: WO2010/115736 A2, 2010 ; Location in patent: Page/Page column 73 ; WO 2010/115736 A2

~57%

methyl 2-amino-5-bromo-3-nitrobenzoate Structure

methyl 2-amino-...

CAS#:636581-61-8

Literature: Charifson, Paul S.; Grillot, Anne-Laure; Grossman, Trudy H.; Parsons, Jonathan D.; Badia, Michael; Bellon, Steve; Deininger, David D.; Drumm, Joseph E.; Gross, Christian H.; LeTiran, Arnaud; Liao, Yusheng; Mani, Nagraj; Nicolau, David P.; Perola, Emanuele; Ronkin, Steven; Shannon, Dean; Swenson, Lora L.; Tang, Qing; Tessier, Pamela R.; Tian, Ski-Kai; Trudeau, Martin; Wang, Tiansheng; Wei, Yunyi; Zhang, Hong; Stamos, Dean Journal of Medicinal Chemistry, 2008 , vol. 51, # 17 p. 5243 - 5263

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Synonyms

2-Amino-5-bromo-3-nitro-benzoic acid methyl ester
Benzoic acid,2-amino-5-bromo-3-nitro-,methyl ester