(-)-N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Leu-)

Modify Date: 2024-01-18 18:52:40

(-)-N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Leu-) structure	Common Name	(-)-N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Leu-)
	CAS Number	63700-39-0	Molecular Weight	1215.53000
	Density	1.24g/cm3	Boiling Point	1541.6ºC at 760mmHg
	Molecular Formula	C₅₈H₁₀₂N₁₆O₁₂	Melting Point	N/A
	MSDS	N/A	Flash Point	886.1ºC

Name	N-[4-amino-1-[[1-[[4-amino-1-oxo-1-[[6,9,18-tris(2-aminoethyl)-15-benzyl-3,12-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctan
Synonym	More Synonyms

Density	1.24g/cm3
Boiling Point	1541.6ºC at 760mmHg
Molecular Formula	C₅₈H₁₀₂N₁₆O₁₂
Molecular Weight	1215.53000
Flash Point	886.1ºC
Exact Mass	1214.79000
PSA	508.82000
LogP	5.21450
Index of Refraction	1.582

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TR1100000

CHEMICAL NAME :: Polymyxin B1, 10-L-leucine

CAS REGISTRY NUMBER :: 63700-39-0

LAST UPDATED :: 198211

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C58-H102-N16-O12

MOLECULAR WEIGHT :: 1215.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 30,1029,1977

Polymyxin B1,10-L-leucine